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Acta pharmaceutica, Vol.62 No.2 Lipanj 2012.
Izvorni znanstveni članak
10.2478/v10007-012-0016-z
Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method
NOURUDDIN WAGEIH ALI
; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
MAHA AHAMD HEGAZY
; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
MOHAMED ABDELKAWY
; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt
EGLAL ABDELAHAMID ABDELALEEM
; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
Puni tekst: pdf (137 KB),
Engleski,
Str. 191 - 200
,
Sažetak
Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results obtained were statistically compared with the reported HPLC methods; no significant difference between the proposed methods and the reported methods was found regarding either accuracy or precision.
Ključne riječi
methocarbamol; diclofenac potassium; ibuprofen; mean centering of ratio spectra; guaifenesin
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