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Survival of Patients Treated with Online Hemodiafiltration Compared to Conventional Hemodialysis

Iva Mesaroš-Devčić ; Dialysis Center Fresenius Medical Care, Delnice, Croatia
Irena Tomljanović ; Dialysis Center Fresenius Medical Care, Delnice, Croatia
Ivana Mikolašević ; University of Rijeka, University Hospital Centre Rijeka, Department of Nephrology and Dialysis, Division of Internal Medicine, Rijeka, Croatia
Štefica Dvornik ; University of Rijeka, University Hospital Centre Rijeka Department of Laboratory Diagnostic, Rijeka, Croatia
Božidar Vujičić ; University of Rijeka, University Hospital Centre Rijeka, Department of Nephrology and Dialysis, Division of Internal Medicine, Rijeka, Croatia
Martina Pavletić-Peršić ; University of Rijeka, University Hospital Centre Rijeka, Department of Nephrology and Dialysis, Division of Internal Medicine, Rijeka, Croatia
Sanjin Rački ; University of Rijeka, University Hospital Centre Rijeka, Department of Nephrology and Dialysis, Division of Internal Medicine, Rijeka, Croatia


Puni tekst: engleski pdf 114 Kb

str. 827-832

preuzimanja: 534

citiraj


Sažetak

Accumulating data from observational studies showed that online hemodiafiltration (OLHDF) might improve sur- vival in chronic hemodialysis (HD) patients. According to this data, the aim of our study was to investigate whether there was a difference in survival of patients treated with OLHDF compared to standard, conventional HD. We included 85 prevalent patients with end-stage renal disease (ESRD) treated with HD as a method of renal replacement therapy (RRT) for more than three months. Patients were previously treated with HD and divided into two groups: in 42 patients new treatment with OLHDF was introduced, and 43 patients were treated with HD. Both groups were followed over a period of 36 months. The study showed significantly better survival of patients treated with OLHDF, compared to the survival of patients treated with HD in the whole study population, as well as in the subgroups of diabetics, of patients who were on RRT with HD for more than five years and of the patients who were older than 65 years. In the nondiabetics, patients who were on RRT for less than five years and in the patients who were younger than 65 years, survival results in the OLHDF group were not significantly better compared to those in the HD group. As in our study, there are accumulating data from observational studies that HDF may improve survival in chronic HD patients, but new, prospective random- ized trials are needed to support evidence about this hypothesis.

Ključne riječi

hemodiafiltration; hemodialysis; mortality; membranes; survival

Hrčak ID:

118275

URI

https://hrcak.srce.hr/118275

Datum izdavanja:

30.9.2013.

Posjeta: 1.065 *