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Imprint Cytology of Gastric Mucosa Biopsy – Fast, Simple and Reliable Method for Detection of Helicobacter Pylori Infection
Ivana Knežević Štromar
Puni tekst: pdf (149 KB),
Str. 171 - 175
The aim of the study was to determine the value of gastric mucosa imprint cytology in the detection of Helicobacter
pylori infection. A total of 182 biopsy specimens, from 182 randomly selected patients undergoing gastroscopy with gastric
mucosa biopsy, were analyzed. Specimens were first submitted to slide imprinting and then formalin fixed for further
routine histopathology. One-hundred and fifty-five specimens proved adequate for definitive comparison of the methods
used for detection of Helicobacter pylori infection. Helicobacter pylori was detected by histopathology in 51 specimens
and by cytology in 54 specimens. Agreement between the findings obtained by the two methods was recorded in 130 of 155
(83.1%) specimens. Positive cytology and negative histology findings were obtained in 14, and vice versa in 11 specimens.
Gastric mucosa imprint cytology provides a useful method for the detection of Helicobacter pylori infection. The method
is advantageous for being fast, simple and inexpensive. When the sample is obtained exclusively for confirmation of the
presence of Helicobacter pylori infection, cytology reduces the time and cost of the procedure, at the same time providing
data on morphological changes of gastric mucosa. Every finding suspect of malignant transformation of the mucosa can
also be verified by histopathology because imprint manipulation causes no damage to the sample.
imprint cytology; Helicobacter pylori; gastric mucosa biopsy
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