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Preparation of 4-aminophenylacetic acid derivatives with promising antimicrobial activity

AHMED H. BEDAIR
FAWZY M. ALI
AHMED M. EL-AGRODY
FATHY A. EID
MOHAMMED A. A. EL-NASSAG
GAMAL EL-SHERBENY

Sažetak

Condensation of 4-APAA with phthalic anhydride gave (dioxoisoindolin-2-yl)phenylacetic acid 1, which is employed as key intermediate in the synthesis of title compounds 2-8. The products have been characterized by analytical and spectral data (IR, 1H NMR, 13C NMR and mass spectra). Antimicrobial activities were also studied and some of these compounds gave promising results.

Ključne riječi

4-aminophenylacetic acid; (dioxoisoindolin-2-yl)phenylacetic acid derivatives; {[(1H-benzo[d]imidazol-2-yl)/(4H-benzo[d][1,3]oxazin-2-yl)methyl]phenyl}isoindoline-1,3-diones, phthaloylhydrazide salts; antimicrobial activity

Hrčak ID:

4540

URI

https://hrcak.srce.hr/4540

Datum izdavanja:

1.9.2006.

Podaci na drugim jezicima: hrvatski

Posjeta: 3.192 *