Pregledni rad

Novel Micro-scale Analytical Devices for On-line Bioprocess Monitoring: A Review

P. Hrnčiřík orcid.org/0000-0002-6533-4541 ; Department of Computing and Control Engineering, Institute of Chemical Technology Prague, Technická 5, 166 28 Praha 6, Czech Republic
J. Náhlík ; Department of Computing and Control Engineering, Institute of Chemical Technology Prague, Technická 5, 166 28 Praha 6, Czech Republic

Sažetak

This review examines the potential of novel micro-scale microfluidic analytical devices – lab-on-a-chip (LOC), micro total analysis systems (µ-TAS) – for on-line monitoring and control of industrial bioprocesses. First, motivation for the current study is presented
and potential benefits from the use of micro-scale analytical devices in bioprocess control and monitoring are outlined. This is followed by a review of the state of the art in the relevant application domain (cell analysis) for novel microfluidic analytical devices. Finally, the conclusion provides a summarizing comparison of the main features of the reported micro-scale analytical devices evaluating their potential applicability for on-line bioprocess monitoring, with the most promising concepts identified.

Ključne riječi

Bioprocess monitoring; lab-on-a-chip; micro total analysis systems; single-cell analysis

Hrčak ID:

62720

URI

https://hrcak.srce.hr/62720

Datum izdavanja:

27.12.2010.

Posjeta: 959 *