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https://doi.org/10.20471/acc.2016.55.01.24

Primary Fibrosarcoma of The Thyroid Gland: Case Report

Nina Dabelić ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Neven Mateša ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Tomislav Jukić ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Željko Soldić ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Davor Kust   ORCID icon orcid.org/0000-0002-8485-9642 ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Angela Prgomet ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Ante Bolanča ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia
Zvonko Kusić ; Clinical Department of Oncology and Nuclear Medicine, Sestre milosrdnice University Hospital Center, Zagreb,Croatia

Fulltext: english, pdf (170 KB) pages 172-175 downloads: 514* cite
APA 6th Edition
Dabelić, N., Mateša, N., Jukić, T., Soldić, Ž., Kust, D., Prgomet, A., ... Kusić, Z. (2016). Primary Fibrosarcoma of The Thyroid Gland: Case Report. Acta clinica Croatica, 55. (1.), 172-175. https://doi.org/10.20471/acc.2016.55.01.24
MLA 8th Edition
Dabelić, Nina, et al. "Primary Fibrosarcoma of The Thyroid Gland: Case Report." Acta clinica Croatica, vol. 55., no. 1., 2016, pp. 172-175. https://doi.org/10.20471/acc.2016.55.01.24. Accessed 21 Sep. 2021.
Chicago 17th Edition
Dabelić, Nina, Neven Mateša, Tomislav Jukić, Željko Soldić, Davor Kust, Angela Prgomet, Ante Bolanča and Zvonko Kusić. "Primary Fibrosarcoma of The Thyroid Gland: Case Report." Acta clinica Croatica 55., no. 1. (2016): 172-175. https://doi.org/10.20471/acc.2016.55.01.24
Harvard
Dabelić, N., et al. (2016). 'Primary Fibrosarcoma of The Thyroid Gland: Case Report', Acta clinica Croatica, 55.(1.), pp. 172-175. https://doi.org/10.20471/acc.2016.55.01.24
Vancouver
Dabelić N, Mateša N, Jukić T, Soldić Ž, Kust D, Prgomet A, et al. Primary Fibrosarcoma of The Thyroid Gland: Case Report. Acta clinica Croatica [Internet]. 2016 [cited 2021 September 21];55.(1.):172-175. https://doi.org/10.20471/acc.2016.55.01.24
IEEE
N. Dabelić, et al., "Primary Fibrosarcoma of The Thyroid Gland: Case Report", Acta clinica Croatica, vol.55., no. 1., pp. 172-175, 2016. [Online]. https://doi.org/10.20471/acc.2016.55.01.24

Abstracts
Due to progressive dyspnea, a male patient aged 59 underwent medical examination in 2003 in a local hospital. Neck ultrasound and fine-needle aspiration biopsy (FNAB) of a suspect lesion in the thyroid gland revealed the presence of a malignant neoplasm, i.e. mesenchymal tumor. Immunocytochemistry for epithelial membrane antigen, chromogranin A and leukocyte common antigen (CD45) was negative, while vimentin and S-100 were positive. The patient was
referred to a university hospital center, where further oncologic work-up was done. Neck ultrasound revealed a tumor in the left lobe of the thyroid, with extension to the aortic arch. After repeated FNAB, cytologic diagnosis of primary thyroid fibrosarcoma was established. Due to the locally advanced and consequently inoperable disease, primary radiotherapy to the neck region (64 Gy in 32 fractions) was applied, followed by 6 cycles of chemotherapy with doxorubicin. After completion of therapy, computed tomography scan demonstrated significant regression of primary disease, but it was still not amenable to surgical treatment. Thus, the decision of the oncology board was active surveillance of the patient. During 9-year follow up, no signs of progression or activity of the disease were found.

Keywords
Fibrosarcoma – radiotherapy; Fibrosarcoma – drug therapy; Thyroid neoplasms – radiotherapy; Thyroid neoplasms – drug therapy

Hrčak ID: 161311

URI
https://hrcak.srce.hr/161311

[croatian]

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