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Review article
https://doi.org/10.21857/9e31lhnddm

Aging, Calorie Restriction and Calorie Restriction Mimetics

Ivana Čepelak ; Department of Medical Biochemistry and Hematology, School of Pharmacy and Biochemistry, University of Zagreb, Croatia
Slavica Dodig ; Department of Medical Biochemistry and Hematology, School of Pharmacy and Biochemistry, University of Zagreb, Croatia
Daniela Čepelak Dodig ; Croatian Institute of Public Health-Department for Toxicology, Zagreb, Croatia

Fulltext: english, pdf (331 KB) pages 41-50 downloads: 263* cite
APA 6th Edition
Čepelak, I., Dodig, S. & Čepelak Dodig, D. (2019). Aging, Calorie Restriction and Calorie Restriction Mimetics. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, (540=48-49), 41-50. https://doi.org/10.21857/9e31lhnddm
MLA 8th Edition
Čepelak, Ivana, et al. "Aging, Calorie Restriction and Calorie Restriction Mimetics." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol. , no. 540=48-49, 2019, pp. 41-50. https://doi.org/10.21857/9e31lhnddm. Accessed 16 Sep. 2021.
Chicago 17th Edition
Čepelak, Ivana, Slavica Dodig and Daniela Čepelak Dodig. "Aging, Calorie Restriction and Calorie Restriction Mimetics." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti , no. 540=48-49 (2019): 41-50. https://doi.org/10.21857/9e31lhnddm
Harvard
Čepelak, I., Dodig, S., and Čepelak Dodig, D. (2019). 'Aging, Calorie Restriction and Calorie Restriction Mimetics', Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, (540=48-49), pp. 41-50. https://doi.org/10.21857/9e31lhnddm
Vancouver
Čepelak I, Dodig S, Čepelak Dodig D. Aging, Calorie Restriction and Calorie Restriction Mimetics. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti [Internet]. 2019 [cited 2021 September 16];(540=48-49):41-50. https://doi.org/10.21857/9e31lhnddm
IEEE
I. Čepelak, S. Dodig and D. Čepelak Dodig, "Aging, Calorie Restriction and Calorie Restriction Mimetics", Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol., no. 540=48-49, pp. 41-50, 2019. [Online]. https://doi.org/10.21857/9e31lhnddm
Fulltext: croatian, pdf (331 KB) pages 41-50 downloads: 128* cite
APA 6th Edition
Čepelak, I., Dodig, S. & Čepelak Dodig, D. (2019). Starenje, kalorijske restrikcije i kalorijsko restrikcijska mimetrika. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, (540=48-49), 41-50. https://doi.org/10.21857/9e31lhnddm
MLA 8th Edition
Čepelak, Ivana, et al. "Starenje, kalorijske restrikcije i kalorijsko restrikcijska mimetrika." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol. , no. 540=48-49, 2019, pp. 41-50. https://doi.org/10.21857/9e31lhnddm. Accessed 16 Sep. 2021.
Chicago 17th Edition
Čepelak, Ivana, Slavica Dodig and Daniela Čepelak Dodig. "Starenje, kalorijske restrikcije i kalorijsko restrikcijska mimetrika." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti , no. 540=48-49 (2019): 41-50. https://doi.org/10.21857/9e31lhnddm
Harvard
Čepelak, I., Dodig, S., and Čepelak Dodig, D. (2019). 'Starenje, kalorijske restrikcije i kalorijsko restrikcijska mimetrika', Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, (540=48-49), pp. 41-50. https://doi.org/10.21857/9e31lhnddm
Vancouver
Čepelak I, Dodig S, Čepelak Dodig D. Starenje, kalorijske restrikcije i kalorijsko restrikcijska mimetrika. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti [Internet]. 2019 [cited 2021 September 16];(540=48-49):41-50. https://doi.org/10.21857/9e31lhnddm
IEEE
I. Čepelak, S. Dodig and D. Čepelak Dodig, "Starenje, kalorijske restrikcije i kalorijsko restrikcijska mimetrika", Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol., no. 540=48-49, pp. 41-50, 2019. [Online]. https://doi.org/10.21857/9e31lhnddm

Abstracts
In line with the increase in the number of older people in the world, the focus of scientists is directed at examining mechanisms of the aging process as well as establishing strategies/interventions in order to slow down aging and achieve longevity. On preclinical testing models, the most effective strategy for this purpose, as well as for the purpose of delaying age-related diseases, nutritional interven-
tion- restriction of calorie (CR) has been demonstrated, but also some alternative forms of calorie restriction. Possible undesirable effects of restriction are still in the testing phase, and it is known that it is generally difficult to implement in humans. Therefore, the new area of research in gerontology has become the discovery and examination of the effects of compounds that mimic the effects of caloric restriction, so called caloric restriction mimetics (CRM). These compounds include numerous compounds of natural origin but also approved medicaments with certain indications. This overview summarizes the latest data on known mechanisms of caloric restriction and more familiar caloric restriction mimetics.

Keywords
aging; caloric restriction; caloric restriction mimetics; sirtuins; resveratrol;

Hrčak ID: 231558

URI
https://hrcak.srce.hr/231558

[croatian]

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