Izvorni znanstveni članak
Histopathological Analysis of UV-B Irradiated Retina by Cavia Coba’ya and with Protection of Transmission Light l 550–600 nm
Božidar Vojniković
Davor Vojniković
Luka Brčić
Sažetak
In 14 experimental Cavia Coba’ya eyes were irradiated with UV-B light, lambda 312 nm, 25 J/cm2 in 15 minute exposure.
Including the transmission of light through optical media: cornea, lens, humor aqueous and vitreous body, and pupil
surface of 7 mm2, we can calculate that in these conditions retina can be really irradiated with 10 J/cm2. The half
number of Cavia Coba’ya was simultaneously irradiated with visible light, lambda of 550–600 nm (1000 Lx). Control
group was 5 Cavia Coba’ya. Two months after irradiation, eyes were enucleated and fixed in 4% formaldehyde. Histopathological
findings showed alterations of all retinal layers: loss of ganglion cells, axons, reduction of photoreceptors,
vacuolar degeneration and hyperplasia of retinal pigment epithelium. In the second group of irradiance, the eyes with
visible light lambda 550–600 nm, all retinal alterations were in 50% decreased.
Ključne riječi
UV-B light; irradiated retina; histopathological findings
Hrčak ID:
27417
URI
Datum izdavanja:
16.1.2007.
Posjeta: 840 *