Original scientific paper
The Renal Parenchyma Evaluation: MAG3 vs. DMSA
Aleksandar Smokvina
Svjetlana Grbac-Ivanković
Neva Girotto
Mirna Subat Dežulović
Giordano Saina
Marina Miletić Barković
Abstract
Scintigraphy with Tc-99m dimercaptosuccinic acid (DMSA) is considered a reference method for assessment of parenchymal lesions and estimation of differential kidney function. The aim of study was to evaluate Tc-99m mercaptoacetyltriglycine (MAG3) dynamic renal scintigraphy for the same purpose. 188 patients, submitted to both studies
within three months, were divided in two groups. In the first, 83 DMSA images were compared to parenchymal phase of MAG3 scintigraphy. Kidney morphology was independently evaluated by four observers. In the second group (N=105), differential function was calculated in MAG3 and DMSA studies and the respective results were compared. Findings corresponded completely in 85% of patients. There were no statistically significant differences between calculated differential function on DMSA and MAG3 images. The results showed that most of parenchymal lesions detected on DMSA scans can be identified on MAG3 parenchymal scans. Both studies can be equally used for the calculation of differential kidney function.
Keywords
renal parenchyma; differential kidney function; mercaptoacetyltriglycine; MAG3; dimercaptosuccinic acid; DMSA
Hrčak ID:
5309
URI
Publication date:
15.12.2005.
Visits: 13.461 *