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hrv Jesu li nam potrebni centri za rak dojke?
eng Do we need breast cancer centers?
Vrdoljak, Eduard; Boban, Marijo; Ban, Marija
Medica Jadertina Vol. 41, No. 3-4, 2011
Hrvatskoj su potrebni centri za rak dojke koji će biti sveobuhvatne baze za dijagnosticiranje, liječenje, praćenje i istraživanje te bolesti. Ustanove u manjim bolnicama trebaju biti sastavni dio šireg tima za liječenje raka dojke. Aktivnosti u takvim centrima izvrsnosti uključuju prije svega timski rad, izradu smjernica, lokalizacijsku onkologiju, trajno usavršavanje stručnjaka, provođenje kliničkih studija, implementaciju novih tehnika liječenja, te kontrolu kvalitete. Organizacija centara izvrsnosti za rak dojke je također u funkciji prilag...
Hrčak ID: 77318


eng Polyethylenimine as a gene delivery tool in triple-negative breast cancer cell line and breast cancer stem cell model
Matovina, Mihaela; Lemmens, Steffi; Kralj, Marijeta; Ester, Katja
Periodicum biologorum Vol. 123, No. 3-4, 2021
Background and purpose: PEI is a cationic polymer able to neutralise negative DNA charges and to condense large genes which makes it suitable for gene delivery in human cells. Despite its low cost, simplicity of use and moderate toxicity, there is still room for broader usage and experimental adjustments, especially in cell lines that are difficult to transfect. In the presented research, we used PEI for the delivery of plasmid DNA into TNBC cell line SUM159 and breast CSC model HMLE-Twist.Material and methods: Cultured cells were transfected w...
Hrčak ID: 279950


eng Unilateral Multicentric Breast Cancer
Fajdić, Josip; Buković, Damir; Gugić, Damir; Habek, Mario; Hojsak, Iva; Buković, Nevija; Herman, Ivan; Stančerić, Tajana
Collegium antropologicum Vol. 27, No. 2, 2003
Clinical characteristics of unilateral multicentric breast cancer (UMBC) were explored depending on aggressiveness, survival rate, disease-free period and local recurrence. The study included 296 women with breast cancer, surgically treated between 1990 and 2001. UMBC was histologically proved in 29 (9.8%) patients. Multicentricity was defined by following criteria: a) tumor with minimum one satellite node in the same or other quadrant of the breast; b) minimum one cut through the breast without tumor cells; c) histopathologically, discon...
Hrčak ID: 28164


eng A patient with metastasis of breast cancer which was originally described as primary colorectal cancer: case report
Glas, A. M.; Čular, K.; Silovski, Tajana; Dedić Plavetić, Natalija
Liječnički vjesnik Vol. 142, No. Supp 5, 2020
Breast cancer metastases can be found in almost all organs in the body - but are most commonly found in the lungs, liver, bones, skin and brain. Metastatic breast cancer often occurs years or decades after initial diagnosis and treatment. In this case report, we will present a 62-year-old patient with metastasis of breast cancer which was originally described as primary colorectal cancer.
Hrčak ID: 251847


eng Protumor effects of proinflammatory mediators in breast cancer
SIROTKOVIĆ-SKERLEV, MAJA; KULIĆ, ANA; BRADIĆ, LADA; ČAČEV, TAMARA
Periodicum biologorum Vol. 114, No. 4, 2012
Inflammation is defined as an enabling characteristic of malignant growth. Many proinflammatory mediators have protumor capabilities. In this review we focus on the protumor effect of cytokines and chemokines in breast cancer. We discuss the role of interleukin 1β, interleukin 6, tumor necrosis factor α, CCL2, CCL5, and CXCL12 and its receptor CXCR4 as typical mediators implicated in breast cancer progression. We also analyze the impact of transcription factor NF-κB. Proinflammatory mediatorswith protumor effects should be considered as thera...
Hrčak ID: 101251


eng ANTIPSYCHOTIC TREATMENT, PROLACTIN, AND BREAST TUMORIGENESIS
De Hert, Marc; Vancampfort, Davy; Stubbs, Brendon; Sabbe, Tine; Wildiers, Hans; Detraux, Johan
Psychiatria Danubina Vol. 28, No. 3, 2016
Background: Over the last decades prolactin (PRL) has gained attention for its possible role in breast tumorigenesis. As all antipsychotics (although differences with respect to PRL elevation are large) have the propensity to induce hyperprolactinemia (HPRL), questions have arisen concerning the influence of PRL-elevating antipsychotic medications on breast cancer risk. Subjects and methods: A literature search (until January 2016), using the MEDLINE database, was conducted for Englishlanguage published clinical studies to identify and synt...
Hrčak ID: 176261


eng PREVALENCE, STRUCTURE AND PREDICTORS OF POSTTRAUMATIC STRESS DISORDER SYMPTOMS IN CROATIAN PATIENTS FOLLOWING BREAST CANCER
Šimunović, Mara; Ljubotina, Damir
Psychiatria Danubina Vol. 32, No. 2, 2020
Background: Breast cancer is the most common cancer in female population worldwide. In the psychological response to the disease some patients may develop Posttraumatic Stress Disorder (PTSD) symptomatology. The aim of this study was to examine the prevalence and structure of PTSD symptoms in Croatian patients following breast cancer and to identify some medical and psychological predictors of severity of these symptoms. Subjects and methods: 97 women, who were one month up to six years post-completion of all primary cancer therapy, participat...
Hrčak ID: 242284


eng Comparison between survivin and ki-67 proliferative index in her-2 positive and triple negative breast carcinoma
Veliki Dalić, Irena; Šarčević, Božena
Hrčak ID: 182466


eng The Level of Serum Pro-Matrix Metalloproteinase-2 as a Prognostic Factor in Patients with Invasive Ductal Breast Cancer
Šturm, Deana; Skoko, Marija; Vučemilo, Tiha; Šarčević, Božena; Puljiz, Mario; Mihaljević, Ivanka
Collegium antropologicum Vol. 38, No. 1, 2014
This paper analyses data of 150 female patients undergoing surgical treatment for invasive ductal breast cancer at the University Hospital for Tumors from January 2006 to January 2007. The control group consisted of 50 healthy women. The patients were classified into three groups, depending on their tumor differentiation, i.e. grade I, II and III tumor groups. Each group consisted of 50 patients. Traditional prognostic factors including: age, tumor size and differentiation grade, axillary lymph node status, presence of distant metastases, stero...
Hrčak ID: 120808


eng Thermography – A Feasible Method for Screening Breast Cancer?
Kolarić, Darko; Herceg, Željko; Nola, Iskra Alexandra; Ramljak, Vesna; Kuliš, Tomislav; Katančić Holjevac, Jadranka; Deutsch, Judith A.; Antonini, Svetlana
Collegium antropologicum Vol. 37, No. 2, 2013
Potential use of thermography for more effective detection of breast carcinoma was evaluated on 26 patients scheduled for breast carcinoma surgery. Ultrasonographic scan, mammography and thermography were performed at the University Hospital for Tumors. Thermographic imaging was performed using a new generation of digital thermal cameras with high sensitivity and resolution (ThermoTracer TH7102WL, NEC). Five images for each patient were recorded: front, right semi-oblique, right oblique, left- semi oblique and left oblique. While mammography de...
Hrčak ID: 104666