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Concentrations of veterinary drug residues in milk from individual farms in Croatia

Nina Bilandžić   ORCID icon orcid.org/0000-0002-0009-5367 ; Department of Veterinary Public Health, Laboratory for Residue Control, Croatian Veterinary Institute, Savska cesta 143, Zagreb, Croatia
Božica Solomun Kolanović
Ivana Varenina
Zorica Jurković

Puni tekst: engleski, pdf (454 KB) str. 260-267 preuzimanja: 1.999* citiraj
APA 6th Edition
Bilandžić, N., Solomun Kolanović, B., Varenina, I. i Jurković, Z. (2011). Concentrations of veterinary drug residues in milk from individual farms in Croatia. Mljekarstvo, 61 (3), 260-267. Preuzeto s https://hrcak.srce.hr/71495
MLA 8th Edition
Bilandžić, Nina, et al. "Concentrations of veterinary drug residues in milk from individual farms in Croatia." Mljekarstvo, vol. 61, br. 3, 2011, str. 260-267. https://hrcak.srce.hr/71495. Citirano 15.11.2019.
Chicago 17th Edition
Bilandžić, Nina, Božica Solomun Kolanović, Ivana Varenina i Zorica Jurković. "Concentrations of veterinary drug residues in milk from individual farms in Croatia." Mljekarstvo 61, br. 3 (2011): 260-267. https://hrcak.srce.hr/71495
Harvard
Bilandžić, N., et al. (2011). 'Concentrations of veterinary drug residues in milk from individual farms in Croatia', Mljekarstvo, 61(3), str. 260-267. Preuzeto s: https://hrcak.srce.hr/71495 (Datum pristupa: 15.11.2019.)
Vancouver
Bilandžić N, Solomun Kolanović B, Varenina I, Jurković Z. Concentrations of veterinary drug residues in milk from individual farms in Croatia. Mljekarstvo [Internet]. 2011 [pristupljeno 15.11.2019.];61(3):260-267. Dostupno na: https://hrcak.srce.hr/71495
IEEE
N. Bilandžić, B. Solomun Kolanović, I. Varenina i Z. Jurković, "Concentrations of veterinary drug residues in milk from individual farms in Croatia", Mljekarstvo, vol.61, br. 3, str. 260-267, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/71495. [Citirano: 15.11.2019.]

Sažetak
A total of 119 raw milk samples collected at individual small milk-producing facilities and collection tanks of milk routes from five counties of east and north continental Croatia were examined for chloramphenicol, sulfonamides, tetracyclines, gentamicin, streptomycin, dihydrostreptomycin, flumequine and enrofloxacin from January to March of 2011. Immunoassay methods used for drug determination were validated according to the guidelines laid down by European Commission Decision 2002/657/EC. Data indicated that the methods are appropriate for the detection of antibiotics measured. Measured mean values (μg L-1) of antibiotics were: 0.005 for chloramphenicol, 3.67 for sulfonamides, 2.83 for tetracyclines, 1.10 for gentamicin, 2.64 for streptomycin, 7.67 for dihydrostreptomycin, 10.4 for flumequine and 4.11 for enrofloxacin. None of samples analyzed showed the presence of veterinary drug residues above the maximum residues levels (MRLs) established by European Union and Croatian legislation. The calculated estimated daily intakes (EDIs) for the average daily milk consumption of 300 mL for an adult in Croatia for examined antibiotics showed levels 20 to 1640 times lower than the values of acceptable daily intakes (ADIs) fixed by European Medicines Agency and World Health Organization. This suggested that toxicological risk associated with the consumption of analysed milk could not be considered a public health issue with regards to these veterinary drugs.

Ključne riječi
milk; veterinary drug residues; ELISA; estimated dietary intake

Hrčak ID: 71495

URI
https://hrcak.srce.hr/71495

[hrvatski]

Posjeta: 2.437 *