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Formation of Adhesions at Surgical Meshes in a Rat Experimental Model
Zdravko Perko
Zenon Pogorelić
Nikica Družijanić
Kanito Bilan
Katarina Vilović
Sažetak
Abdominal wall hernias are surgical problem that are easily solved with laparoscopic surgery. The determining factor
for the success of the operation is the right choice and use of surgical mesh as the support material. The most common
complication of surgical mesh placement is the formation of adhesions. Aim of this paper is to determine whether there is
a statistic difference in formation of adhesions between different surgical meshes in lab environment. Wistar rats were
used as the experimental model. After the anaesthesia a 1x1 cm defect of the abdominal wall was made, but the skin was
left intact. The mesh was placed directly on the internal organs. The experiment considered four different mesh types. After
set time periods of one, two or four weeks the animals were sacrificed and the amount of formed adhesions were evaluated
based on the modified Diamond scale. Immediately after the first week we found a statistically significant difference
in the adhesion occurrence rate between compared materials. The smallest amount of adhesions was caused by polypropylen
+ polydoksanon mesh, and the most by polypropilen mesh. Polypropylen + polyglactin mesh showed significant
reduction of adhesion formation between the tested weeks. We can conclude that polypropylen + polydoxanon meshes
are superior for ventral hernia operation, because those defects are in close contact with the internal organs and it is
very important to have the smallest amount of adhesions.
Ključne riječi
abdominal adhesions; adhesion prevention; surgical mesh; rats; abdominal wall hernia
Hrčak ID:
72196
URI
Datum izdavanja:
30.9.2011.
Posjeta: 921 *