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Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects

Renata Gržetić-Lenac
Maja Merlak
Tihomir Balog
Marijana Bilen Babić
Iva Dekaris

Puni tekst: engleski, pdf (61 KB) str. 167-169 preuzimanja: 290* citiraj
APA 6th Edition
Gržetić-Lenac, R., Merlak, M., Balog, T., Bilen Babić, M. i Dekaris, I. (2011). Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects. Collegium antropologicum, 35 - supplement 2 (2), 167-169. Preuzeto s https://hrcak.srce.hr/72258
MLA 8th Edition
Gržetić-Lenac, Renata, et al. "Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects." Collegium antropologicum, vol. 35 - supplement 2, br. 2, 2011, str. 167-169. https://hrcak.srce.hr/72258. Citirano 28.11.2020.
Chicago 17th Edition
Gržetić-Lenac, Renata, Maja Merlak, Tihomir Balog, Marijana Bilen Babić i Iva Dekaris. "Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects." Collegium antropologicum 35 - supplement 2, br. 2 (2011): 167-169. https://hrcak.srce.hr/72258
Harvard
Gržetić-Lenac, R., et al. (2011). 'Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects', Collegium antropologicum, 35 - supplement 2(2), str. 167-169. Preuzeto s: https://hrcak.srce.hr/72258 (Datum pristupa: 28.11.2020.)
Vancouver
Gržetić-Lenac R, Merlak M, Balog T, Bilen Babić M, Dekaris I. Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects. Collegium antropologicum [Internet]. 2011 [pristupljeno 28.11.2020.];35 - supplement 2(2):167-169. Dostupno na: https://hrcak.srce.hr/72258
IEEE
R. Gržetić-Lenac, M. Merlak, T. Balog, M. Bilen Babić i I. Dekaris, "Transplantation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects", Collegium antropologicum, vol.35 - supplement 2, br. 2, str. 167-169, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/72258. [Citirano: 28.11.2020.]

Sažetak
Amniotic membrane transplantation (AMT) leads to reduction of inflammatory symptoms and causes faster epithelisation
in corneal ulcers and persistant epithelial defect. 21 patients with corneal ulcer (n=18) or non-healing epithelial
defect (n=3) unresponsive to conventional treatment were included in the study. All patients were treated by AMT.
Corneal epithelial cells in patients suffering from corneal ulcer secreted 3.51±1.79 of IL-1a, 64.27±31.53 pg/mL of TNFa
and 209.07±201.82 pg/mL of VEGF. Levels of all 3 investigated cytokines were significantly higher as compared to controls
(p<0.005). Amniotic membranes that were used contained 775.69±613.98 pg/mL of IL-1ra, 0.036±0.033 pg/mL of
sTNF and 175.01±166.63 pg/mL of VEGF-R. Supporting effect of the AMT could be explained by the fact that AM secretes
its natural antinflammatory antagonists IL-1ra, sTNF and VEGF-R.

Ključne riječi
amniotic membrane transplantation; corneal ulcer; persistent epithelial defects; cytokines

Hrčak ID: 72258

URI
https://hrcak.srce.hr/72258

Posjeta: 509 *