Medicina, Vol. 47 No. 4, 2011.
Pregledni rad
Cytomorphologic diagnostics of acute myeloid leukemia – the World Health Organization classification
Sunčica Ries
; Klinički zavod za patologiju i citologiju, KBC Zagreb, Zagreb, Hrvatska
Sažetak
World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues incorporates morphologic, cytochemical, immunophenotypic, genetic and clinical informations into diagnostic algorithms for myeloid neoplasms. Cytomorphologic assessment of more than 20% blasts from 200-cell leukocyte differential counts of the peripheral blood smear and 500-cell differential counts of all cells in the bone marrow aspirate stained with May-Gruenwald Giemsa (MGG), is considered to be an acute leukemia. Along with cytomorphologic findings, the diagnosis is established with immunophenotypic, genetic and molecular findings, but clinical factors must be taken into consideration when deciding the onset of therapy.
Ključne riječi
acute myeloid leukemia; cytomorphology; WHO
Hrčak ID:
76666
URI
Datum izdavanja:
1.12.2011.
Posjeta: 6.157 *