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Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle

Snježana Bajek
Marina Nikolić
Tamara Šoić-Vranić
Goran Bajek
Olga Cvijanović
Gordana Starčević-Klasan

Puni tekst: engleski, pdf (196 KB) str. 167-172 preuzimanja: 165* citiraj
APA 6th Edition
Bajek, S., Nikolić, M., Šoić-Vranić, T., Bajek, G., Cvijanović, O. i Starčević-Klasan, G. (2012). Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle. Collegium antropologicum, 36 (1), 167-172. Preuzeto s https://hrcak.srce.hr/78808
MLA 8th Edition
Bajek, Snježana, et al. "Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle." Collegium antropologicum, vol. 36, br. 1, 2012, str. 167-172. https://hrcak.srce.hr/78808. Citirano 17.11.2019.
Chicago 17th Edition
Bajek, Snježana, Marina Nikolić, Tamara Šoić-Vranić, Goran Bajek, Olga Cvijanović i Gordana Starčević-Klasan. "Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle." Collegium antropologicum 36, br. 1 (2012): 167-172. https://hrcak.srce.hr/78808
Harvard
Bajek, S., et al. (2012). 'Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle', Collegium antropologicum, 36(1), str. 167-172. Preuzeto s: https://hrcak.srce.hr/78808 (Datum pristupa: 17.11.2019.)
Vancouver
Bajek S, Nikolić M, Šoić-Vranić T, Bajek G, Cvijanović O, Starčević-Klasan G. Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle. Collegium antropologicum [Internet]. 2012 [pristupljeno 17.11.2019.];36(1):167-172. Dostupno na: https://hrcak.srce.hr/78808
IEEE
S. Bajek, M. Nikolić, T. Šoić-Vranić, G. Bajek, O. Cvijanović i G. Starčević-Klasan, "Influence of Hyperbaric Oxygen Treatment on Myogenic Transcriptional Factors of Denervated Rat Muscle", Collegium antropologicum, vol.36, br. 1, str. 167-172, 2012. [Online]. Dostupno na: https://hrcak.srce.hr/78808. [Citirano: 17.11.2019.]

Sažetak
The aim of this study was to determine whether hyperbaric oxygen (HBO2) treatment influences the expression of transcriptional myogenic factors in denervated rat’s extensor digitorum longus muscle. Thus, expressing regulatory myogenic factors MyoD and myogenin were analyzed in denervated muscles (up to 30 days). Second group of denervated rats were afterwards treated with HBO2. Normal, innervated muscles were used as controls. Western blot analysis showed a significant upregulation of MyoD and myogenin proteins in denervated muscle during this period. Denervated muscles of rats exposed to HBO2 treatment had also significant upregulation of both transcriptional factors but the treatment had not altered their expression. The immunohistochemical analysis showed MyoD and myogenin protein expression through this period in the denervated, untreated muscles and in denervated muscles of rats treated with HBO2, too. One month denervation caused a reduction in muscle fiber cross-sectional area. The treatment with HBO2 had not reduced the degree of atrophy. The protocol of hyperbaric oxygenation (HBO) applied in this study had no beneficial effect either on transcriptional myogenic factors or on atrophy of denervated rat muscle.

Ključne riječi
hyperbaric oxygen; denervation; myogenic transcriptional factors; rat

Hrčak ID: 78808

URI
https://hrcak.srce.hr/78808

Posjeta: 298 *