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Congenital Cytomegalovirus Infection

Ester Pernjak Pugel ; Zavod za histologiju i embriologiju, Medicinski fakultet Sveučilišta u Rijeci, Rijeka, Hrvatska
Đurđica Cekinović ; Zavod za histologiju i embriologiju, Medicinski fakultet Sveučilišta u Rijeci, Rijeka, Hrvatska

Puni tekst: hrvatski, pdf (315 KB) str. 23-29 preuzimanja: 1.315* citiraj
APA 6th Edition
Pernjak Pugel, E. i Cekinović, Đ. (2012). Prirođena citomegalovirusna infekcija. Medicina Fluminensis, 48 (1), 23-29. Preuzeto s https://hrcak.srce.hr/80227
MLA 8th Edition
Pernjak Pugel, Ester i Đurđica Cekinović. "Prirođena citomegalovirusna infekcija." Medicina Fluminensis, vol. 48, br. 1, 2012, str. 23-29. https://hrcak.srce.hr/80227. Citirano 11.04.2021.
Chicago 17th Edition
Pernjak Pugel, Ester i Đurđica Cekinović. "Prirođena citomegalovirusna infekcija." Medicina Fluminensis 48, br. 1 (2012): 23-29. https://hrcak.srce.hr/80227
Harvard
Pernjak Pugel, E., i Cekinović, Đ. (2012). 'Prirođena citomegalovirusna infekcija', Medicina Fluminensis, 48(1), str. 23-29. Preuzeto s: https://hrcak.srce.hr/80227 (Datum pristupa: 11.04.2021.)
Vancouver
Pernjak Pugel E, Cekinović Đ. Prirođena citomegalovirusna infekcija. Medicina Fluminensis [Internet]. 2012 [pristupljeno 11.04.2021.];48(1):23-29. Dostupno na: https://hrcak.srce.hr/80227
IEEE
E. Pernjak Pugel i Đ. Cekinović, "Prirođena citomegalovirusna infekcija", Medicina Fluminensis, vol.48, br. 1, str. 23-29, 2012. [Online]. Dostupno na: https://hrcak.srce.hr/80227. [Citirano: 11.04.2021.]

Sažetak
Cytomegalovirus (CMV) infection is the most common congenital viral infection in humans and the major cause of wide-spread encephalitis and developmental abnormalities of the newborn brain which can lead to several neurological consequences. Infection with the human CMV (HCMV) in patients with normal immune function does not cause a clinically manifest disease. As the HCMV infection in pregnancy is often unrecognized, it represents an additional risk for development of congenital HCMV infection. Beside the direct cytopathic effect of CMV on neurons during neurogenesis, the presence of the virus in brain parenchyme leads to the activation of host inflammatory response and development of pathohistological lesions. Therefore, further studies should be focused on development of safe and effective vaccines and drugs that will reduce the risk of maternal infection and in case of virus transfer from mother to child have the ability to prevent the development of congenital CMV infection.

Ključne riječi
brain; CMV infection; congenital infection

Hrčak ID: 80227

URI
https://hrcak.srce.hr/80227

[hrvatski]

Posjeta: 1.743 *