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Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race

Roberto Corsetti ; Liquigas-Cannondale Pro-cycling Team, Medical Board, Faenza, Italia
Giovanni Lombardi ; I.R.C.C.S. Istituto Ortopedico Galeazzi, Milano, Italia
Alessandra Barassi ; Dipartimento di Medicina, Chirurgia e Odontoiatria, University of Milano, Milano, Italia
Patrizia Lanteri ; I.R.C.C.S. Istituto Ortopedico Galeazzi, Milano, Italia
Alessandra Colombini ; I.R.C.C.S. Istituto Ortopedico Galeazzi, Milano, Italia
Gianvico Melzi D’Eril ; Dipartimento di Medicina, Chirurgia e Odontoiatria, University of Milano, Milano, Italia
Giuseppe Banfi ; I.R.C.C.S. Istituto Ortopedico Galeazzi, Milano, Italia; Chair of Clinical Biochemistry, School of Medicine University of Milano, Milano, Italia

Puni tekst: engleski, pdf (186 KB) str. 237-246 preuzimanja: 433* citiraj
APA 6th Edition
Corsetti, R., Lombardi, G., Barassi, A., Lanteri, P., Colombini, A., D’Eril, G.M. i Banfi, G. (2012). Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race. Biochemia Medica, 22 (2), 237-246. Preuzeto s https://hrcak.srce.hr/83228
MLA 8th Edition
Corsetti, Roberto, et al. "Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race." Biochemia Medica, vol. 22, br. 2, 2012, str. 237-246. https://hrcak.srce.hr/83228. Citirano 26.01.2021.
Chicago 17th Edition
Corsetti, Roberto, Giovanni Lombardi, Alessandra Barassi, Patrizia Lanteri, Alessandra Colombini, Gianvico Melzi D’Eril i Giuseppe Banfi. "Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race." Biochemia Medica 22, br. 2 (2012): 237-246. https://hrcak.srce.hr/83228
Harvard
Corsetti, R., et al. (2012). 'Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race', Biochemia Medica, 22(2), str. 237-246. Preuzeto s: https://hrcak.srce.hr/83228 (Datum pristupa: 26.01.2021.)
Vancouver
Corsetti R, Lombardi G, Barassi A, Lanteri P, Colombini A, D’Eril GM i sur. Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race. Biochemia Medica [Internet]. 2012 [pristupljeno 26.01.2021.];22(2):237-246. Dostupno na: https://hrcak.srce.hr/83228
IEEE
R. Corsetti, et al., "Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race", Biochemia Medica, vol.22, br. 2, str. 237-246, 2012. [Online]. Dostupno na: https://hrcak.srce.hr/83228. [Citirano: 26.01.2021.]

Sažetak
Introduction: The study of cardiac response to strenuous and continuous exercise is crucial to un-derstanding the physiology of endurance. N-terminal proB-type natriuretic peptide (NT-proBNP) is a potential marker for monitoring myocardial wall stress, and troponins (TnT and TnI) are widely used in the diagnosis of cardiac ischemia and infarction. Strenuous exercise may generate transitory ische-mia, myocardial stress, and diastolic left ventricular dysfunction, inducing the increased production of both these biomarkers. We measured changes in NT-proBNP and TnT in elite cyclists during a 3-week stage race, a model of strenuous exercise.
Materials and methods: The study population was 9 professional cyclists participating in the 2011 Giro d’Italia. Pre-analytical and analytical phases scrupulously followed official recommendations. Anthropometric data, net energy expenditure and cardiac indexes (rate, diastolic and systolic blood pressure) were recorded. Blood samples were drawn pre-race (day -1) and at days 12 and 22; NT-proBNP and highly sensitive-troponin (Hs-TnT) concentrations were assayed and corrected for plas-ma volume changes.
Results: Body-mass index decreased and energy expenditure increased by 52% during the race. NT-proBNP concentrations increased [day -1: 23.52 ng/L (9.67-34.33); day 12: 63.46 ng/L (22.15-93.31); P = 0.039; day 22: 89.26 ng/L (34.66-129.78) vs. day -1; P < 0.001] and correlated with heart rate (r = -0.51; P = 0.006), systolic pressure (r = 0.39; P = 0.046) and energy expenditure (r = 0.70; P < 0.001). TnT concentrations did not vary, but a widened TnT amplitude distribution was observed.
Conclusions: Increases in NT-proBNP correlated with higher energy expenditure over a 3-week cy-cling stage race, possibly indicating myocardial stress.

Ključne riječi
amino-terminal pro-brain natriuretic peptide; troponin T; physical endurance; energy expenditure

Hrčak ID: 83228

URI
https://hrcak.srce.hr/83228

Posjeta: 799 *