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Original scientific paper

Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation

Ruza Stević
Dragana Jovanović
Ljudmila Nagorni Obradović
Branislava Milenković
Vesna Skodrić-Trifunović
Ivana Stanković

Fulltext: english, pdf (195 KB) pages 505-511 downloads: 206* cite
APA 6th Edition
Stević, R., Jovanović, D., Nagorni Obradović, Lj., Milenković, B., Skodrić-Trifunović, V. & Stanković, I. (2012). Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation. Collegium antropologicum, 36 (2), 505-511. Retrieved from https://hrcak.srce.hr/84811
MLA 8th Edition
Stević, Ruza, et al. "Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation." Collegium antropologicum, vol. 36, no. 2, 2012, pp. 505-511. https://hrcak.srce.hr/84811. Accessed 10 Apr. 2020.
Chicago 17th Edition
Stević, Ruza, Dragana Jovanović, Ljudmila Nagorni Obradović, Branislava Milenković, Vesna Skodrić-Trifunović and Ivana Stanković. "Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation." Collegium antropologicum 36, no. 2 (2012): 505-511. https://hrcak.srce.hr/84811
Harvard
Stević, R., et al. (2012). 'Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation', Collegium antropologicum, 36(2), pp. 505-511. Available at: https://hrcak.srce.hr/84811 (Accessed 10 April 2020)
Vancouver
Stević R, Jovanović D, Nagorni Obradović Lj, Milenković B, Skodrić-Trifunović V, Stanković I. Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation. Collegium antropologicum [Internet]. 2012 [cited 2020 April 10];36(2):505-511. Available from: https://hrcak.srce.hr/84811
IEEE
R. Stević, D. Jovanović, Lj. Nagorni Obradović, B. Milenković, V. Skodrić-Trifunović and I. Stanković, "Wegener’s Granulomatosis: Clinico-Radiological Finding at Initial Presentation", Collegium antropologicum, vol.36, no. 2, pp. 505-511, 2012. [Online]. Available: https://hrcak.srce.hr/84811. [Accessed: 10 April 2020]

Abstracts
Diagnosis of Wegener’s granulomatosis at the early stage is difficult because of the nonspecific symptoms which
mimic other disorders. The aim of this paper is to describe clinical and radiological features of Wegener’s granulomatosis
(WG) in a Serbian population at initial presentation. A retrospective review of 37 patient's case records was carried
out. All those patients were diagnosed with WG and they attended the Institute for lung diseases in Belgrade over
the period of 15 years. There were 20 males and 17 females, ranging in age from 18 to 73 years (mean age 46.2 years).
The mean period from the onset of the first symptoms to diagnosis of WG was 4.59±6.15 months. The criteria of American
College of Rheumatology were fulfilled in all patients. Twenty-five of 37 patients had systemic, generalized form of
WG and while 12 of them had a limited involvement of upper and lower respiratory system. The frequency of different
system involvement was: upper respiratory tract 64.8%, lower respiratory tract 100%, kidneys 67.5%, musculoskeletal
system 40.5%, skin 27.2%, eyes 8.1%, and nervous system two patients. ANCA (antineutrophil cytoplasmic antibodies)
test was positive in 32((86.5%) patients, and negative in 5(13.5%). All patients were ANA negative. Histological evidence
of granulomatous vasculitis was obtained in 34(91.9%), whereas in three patients the diagnosis was based on clinical
manifestations and positive c-ANCA test. There are minor variations in our data when compared with those reported in
literature.

Keywords
Wegener’s granulomatosis; radiology; kidney; lung lesion

Hrčak ID: 84811

URI
https://hrcak.srce.hr/84811

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