hrcak mascot   Srce   HID

Izvorni znanstveni članak

Local Therapy as Basic Anti-Aging Prevention

Nevia Delalle-Lozica

Puni tekst: engleski, pdf (179 KB) str. 529-536 preuzimanja: 1.011* citiraj
APA 6th Edition
Delalle-Lozica, N. (2010). Local Therapy as Basic Anti-Aging Prevention. Acta clinica Croatica, 49 (4), 529-536. Preuzeto s https://hrcak.srce.hr/84839
MLA 8th Edition
Delalle-Lozica, Nevia. "Local Therapy as Basic Anti-Aging Prevention." Acta clinica Croatica, vol. 49, br. 4, 2010, str. 529-536. https://hrcak.srce.hr/84839. Citirano 14.04.2021.
Chicago 17th Edition
Delalle-Lozica, Nevia. "Local Therapy as Basic Anti-Aging Prevention." Acta clinica Croatica 49, br. 4 (2010): 529-536. https://hrcak.srce.hr/84839
Harvard
Delalle-Lozica, N. (2010). 'Local Therapy as Basic Anti-Aging Prevention', Acta clinica Croatica, 49(4), str. 529-536. Preuzeto s: https://hrcak.srce.hr/84839 (Datum pristupa: 14.04.2021.)
Vancouver
Delalle-Lozica N. Local Therapy as Basic Anti-Aging Prevention. Acta clinica Croatica [Internet]. 2010 [pristupljeno 14.04.2021.];49(4):529-536. Dostupno na: https://hrcak.srce.hr/84839
IEEE
N. Delalle-Lozica, "Local Therapy as Basic Anti-Aging Prevention", Acta clinica Croatica, vol.49, br. 4, str. 529-536, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/84839. [Citirano: 14.04.2021.]

Sažetak
Skin, the largest organ of the body, is the organ in which changes associated with aging are most visible. Intrinsic (chronologic) skin aging is characterized by atrophy of the skin with loss of elasticity and slowed metabolic activity. With superposition of environmental damage, particularly exposure to ultraviolet radiation (photodamage) on the intrinsic aging, the process results, at least initially, in hypertrophic repair response with thickened epidermis and increased melanogenesis. Even more striking changes occur in the dermis, i.e. massive elastosis (deposition of abnormal elastic fibers), collagen degeneration, and twisted, dilated microvasculature. Regular use of a sunscreen alone appears to allow for some repair as well as protection from further photodamage. Local anti-aging therapy has been shown to partially reverse the clinical and histologic changes induced by the combination of sunlight exposure and chronologic aging. Histologic changes in the epidermis and dermis noted after 12 months suggest repair of photodamage by reconstitution of rete pegs, repair of keratinocyte ultrastructural damage, more even distribution of melanocytes and melanin pigment, deposition of new papillary dermal collagen, and improvements in vasculature. Hyperkeratinization is normalized, while epidermal thickness and dermal glycosaminoglycan content are increased. Briefly, many of the unwanted changes can be improved by topical therapy.

Ključne riječi
skin aging; photoaging; local therapy; hyaluronic acid; collagen UV rays; photoprotection; wrinkles; pigmentation

Hrčak ID: 84839

URI
https://hrcak.srce.hr/84839

[hrvatski]

Posjeta: 1.653 *