Multi-resistant bacteria as causative agents of urinary tract infections
Arjana Tambić Andrašević Saša Andrašević
Puni tekst nije dostupan.
Sažetak The most frequent causative agent in urinary tract infections (UTIs) is Escherichia coli, which has long been considered naturally sensitive to many antibiotics. In Croatia, resistance in E. coli to ampicillin has been approximately 50% and to co-trimoxazole over 20% for many years now. In complicated, especially health care-associated UTIs, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumanii are more frequent isolates. In Croatia, K. pneumoniae resistance to III generation cephalosporins is 34%, and sporadic carbapenem-resistant isolates were detected in the last two years. While carbapenem resistance in P. aeruginosa has been significant for some time, being 12% in 2010, carbapenem resistance in A. baumanii is on the rise and has reached 34%. It is extremely important to contain the spread of multi-resistant strains once they emerge and to use antibiotics rationally. ISKRA Croatian national guidelines offer help in selecting an antibiotic that is efficient in particular UTI category taking care that broad spectrum antibiotics are saved for severe infections.