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Human papillomaviruses and cervical cancer

Magdalena Grce
Mihaela Matovina

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The infection with oncogenic (high-risk) types of human papillomavirus (HPV) causes nearly all cervical squamous cancers and cervical adenocarcinomas. That is why the prevention of cervical cancer is generally based on the suppression of infection by HPV types 16 and 18, which together cause almost 70% of cervical cancer cases. Therefore, the primary prevention of cervical cancer can be achieved by the use of prophylactic vaccine aimed at these two oncogenic HPV types. In addition, HPV testing that detects women at high risk for the development of precancerous lesions and cancer improves Pap smear screening results.

Ključne riječi
early detection of cancer; human papillomavirus 16; human papillomavirus 18; mass screening; papillomavirus vaccines; uterine cervical neoplasms

Hrčak ID: 86631



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