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A CASE CONTROL STUDY OF DIET AND THE RISKS OF BREAST CANCER
Nurka Pranjić
orcid.org/0000-0001-6145-1137
; Katedra za Medicinu rada, Medicinski fakultet Univerziteta u Tuzli, Univerzitetska 1, 75 000 Tuzla
Ibrahim Gledo
; Katedra za Porodičnu medicinu, Zdravstveni fakultet Univerziteta u Zenici, Crkvice 67, 72 000
Sažetak
Background: Numerous studies have observed dietary risk factors for breast cancer. We investigated the association between dietary intake factors as breast cancer risks or protectors in a case-control study in industrial Zenica- Doboj Canton in Bosnia and Herzegovina.
Methods: A case control study and family ambulatory based survey was completed by 200 female patients. New breast cancer among subjects of experimental groups (n=100) was diagnosed from 1. January 2003 to 31 December 2007 using institutional clinically procedure to breast cancer diagnosis. Data were obtained using a self- rated questionnaire on diet and various food intakes as breast cancer predictor or protector. Logistic regression was used to compute odds ratios (ORs) and 95% confidence intervals (CI) and a full assessment of confounding was included in analysis.
Results: There are significant differences between groups for physical activity (P=0.016), secure existence (P=0.004) and exposure to CT (0.014). Among nutritional factors, the one serving as predictor for development of breast carcinoma was deficiency of intake of blueberry, blackberry and raspberry (β=0.165, CI 95% -0.001-0.143, P=0.050) and intake Vitamine A, C, and E more than 2 times yearly in suplements (β=0.307, CI 95% 0.037-0.098, P=0.001). In case of reduced physical activity significant protectors can be fibers in food (β= -0.338, CI 95% -0.250-0.015, P=0.028) and often intake fruits as are grapefruit, banana or apple (β=0.523, CI 95% -0.051-
0.298, P=0.007).
Conclusion: Breast cancer can be prevented by consumption of adequate (healthy) food intake rich for protective factors especially: fibers in food, fruit juice, olives, fruit and vegetable, carrots and garlic. But not recomend intake of Vitamin A,C, and E in supplement because it cuold be predictor of breast cancer.
Ključne riječi
breast cancer; dietary factors; protectors; predictors
Hrčak ID:
87469
URI
Datum izdavanja:
30.9.2012.
Posjeta: 4.026 *