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Experimental Study of δ-ALA-PDT in the Treatment in BXSB Lupus-Prone Mice

Zhou Surong ; Department of Dermatology, Affiliated Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong Province
Liu Chuanyu
Xv Shizheng

Puni tekst nije dostupan.

Sažetak
Extracorporeal photochemotherapy can correct immune
disease and treat many autoimmune diseases. The aim of this study was
to investigate the effects of delta-aminolevulinic acid photodynamic
therapy (δ-ALA-PDT) on BXSB mouse. The 24-h urine protein, titers of serum
antinuclear antibodies, peripheral blood lymphocyte apoptosis and
deposition of immune complex in renal glomeruli were determined in
BXSB mice after δ-ALA-PDT treatment. Results showed that δ-ALA-PDT
treatment could reduce 24-h urine protein, titers of serum antinuclear
antibodies, and deposition of immune complex in renal glomeruli. The
δ-ALA-PDT treatment could also lead to significant increase in the rate of
peripheral blood lymphocytes

Ključne riječi
photochemotherapy; systemic lupus erythematosus; proteinuria; antinuclear antibodies; apoptosis; immune complex diseases

Hrčak ID: 89059

URI
https://hrcak.srce.hr/89059

Posjeta: 185 *