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Stroke- the most important cause of the newly diagnosed epilepsy in the elderly

SNJEŽANA MIŠKOV ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia
JELENA BOŠNJAK ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia
MARINA ROJE-BEDEKOVIĆ ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia
IVAN MIKULA ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia
LIDIJA DEŽMALJ-GRBELJA ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia
LENKA KOPAČEVIĆ ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia
VIDA DEMARIN ; Medical Centre Aviva, Nemetova 2, Zagreb, Croatia
VANJA BAŠIĆ-KES ; Department for Neurology, University Hospital „Sestre milosrdnice“, Vinogradska cesta 29, 10 000 Zagreb, Croatia

Puni tekst: engleski, pdf (156 KB) str. 429-433 preuzimanja: 967* citiraj
APA 6th Edition
MIŠKOV, S., BOŠNJAK, J., ROJE-BEDEKOVIĆ, M., MIKULA, I., DEŽMALJ-GRBELJA, L., KOPAČEVIĆ, L., ... BAŠIĆ-KES, V. (2012). Stroke- the most important cause of the newly diagnosed epilepsy in the elderly. Periodicum biologorum, 114 (3), 429-433. Preuzeto s https://hrcak.srce.hr/96719
MLA 8th Edition
MIŠKOV, SNJEŽANA, et al. "Stroke- the most important cause of the newly diagnosed epilepsy in the elderly." Periodicum biologorum, vol. 114, br. 3, 2012, str. 429-433. https://hrcak.srce.hr/96719. Citirano 26.07.2021.
Chicago 17th Edition
MIŠKOV, SNJEŽANA, JELENA BOŠNJAK, MARINA ROJE-BEDEKOVIĆ, IVAN MIKULA, LIDIJA DEŽMALJ-GRBELJA, LENKA KOPAČEVIĆ, VIDA DEMARIN i VANJA BAŠIĆ-KES. "Stroke- the most important cause of the newly diagnosed epilepsy in the elderly." Periodicum biologorum 114, br. 3 (2012): 429-433. https://hrcak.srce.hr/96719
Harvard
MIŠKOV, S., et al. (2012). 'Stroke- the most important cause of the newly diagnosed epilepsy in the elderly', Periodicum biologorum, 114(3), str. 429-433. Preuzeto s: https://hrcak.srce.hr/96719 (Datum pristupa: 26.07.2021.)
Vancouver
MIŠKOV S, BOŠNJAK J, ROJE-BEDEKOVIĆ M, MIKULA I, DEŽMALJ-GRBELJA L, KOPAČEVIĆ L i sur. Stroke- the most important cause of the newly diagnosed epilepsy in the elderly. Periodicum biologorum [Internet]. 2012 [pristupljeno 26.07.2021.];114(3):429-433. Dostupno na: https://hrcak.srce.hr/96719
IEEE
S. MIŠKOV, et al., "Stroke- the most important cause of the newly diagnosed epilepsy in the elderly", Periodicum biologorum, vol.114, br. 3, str. 429-433, 2012. [Online]. Dostupno na: https://hrcak.srce.hr/96719. [Citirano: 26.07.2021.]

Sažetak
About 35% of all newly diagnosed epileptic seizures in people older than
60 years are caused by stroke. The incidence of the early epileptic seizures is 2.4–5.4%, and for the late seizures 3–4.5%. Seizures after stroke are most often simple partial seizures with or without secondary generalization, and less often complex partial seizures. In early seizure these are acute biochemical cellular changes, and in late seizures gliosis. Althoung the risk for developing epilepsy was 17–35% after early seizures, the risk of developing epilepsy after late seizures increased to 65–90%. Combination of coronary heart disease,
hypertonia and cardiovascular disease occur in 65% of patients over 75 year old. Intrah spitalmortality in patients with stroke with epileptic seizures was 37.9% compared to patients without seizures (14.4%). Early seizures cause highermortality than late seizures which can be explained by sinergistic effect of of the damaged tissue due to the seizure and vascular ischaemia. European authors in 2007 indicate that lavetiracetam, lamotrigine and gabapentin were first line drugs, followed by topiramate and valproate in elderly patients.
Oxcarbazepine and carbamazepine were not highly recommended because of the associated hyponatremia, cardiac disorders and interaction potentials. The standard antiepileptic drug for focal epilepsy is still carbamazepine, and valproate is most commonly used for generalized epilepsy- even in older patients. Epidemiological studies on epilepsy treatment in the elderly show steady increase in the number of patients. Therefore, elderly patients require special attention. Monotherapy in lowdoses is often sufficient, enzyme inducing
drug are used too frequently.

Ključne riječi
epilepsy; epileptic seizures; stroke; elderly

Hrčak ID: 96719

URI
https://hrcak.srce.hr/96719

Posjeta: 1.203 *