Sažetak Functional transcranial Doppler sonography constitutes a complementary
perfusion-sensitive neuroimaging tool measuring cerebral perfusion
changes due to neural activation. The method is based on the close linkage between local neural activity and regional cerebral blood flow changes. It also provides high temporal resolution, which allows the assessment of the fast changes in flow parameters resulting from change in neural activity. Additional advantages of the technique are its noninvasiveness, low cost, and mobility,which makes it ideal for follow-up investigations in adult and pediatric patients or healthy subjects. Recent advantages in the technique have produced a large number of fTCD studies on the organization of different motor, sensory, endothelial, vasomotor and cognitive functions in the brain. In this article the scientific and clinical applications of fTCD of our research group are presented.