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Original scientific paper

A Cytotoxic and Genotoxic Study of Magnetic Sm C05 Alloys

Vlado Carek ; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Magdalena Eger ; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska
Ružica Požgaj ; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska
Nada Horš ; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska

Fulltext: croatian, pdf (8 MB) pages 239-244 downloads: 270* cite
APA 6th Edition
Carek, V., Eger, M., Požgaj, R. & Horš, N. (1992). Citotoksično i genotoksično ispitivanje magnetskih slitina Sm C05. Acta stomatologica Croatica, 26 (4), 239-244. Retrieved from https://hrcak.srce.hr/100766
MLA 8th Edition
Carek, Vlado, et al. "Citotoksično i genotoksično ispitivanje magnetskih slitina Sm C05." Acta stomatologica Croatica, vol. 26, no. 4, 1992, pp. 239-244. https://hrcak.srce.hr/100766. Accessed 16 Oct. 2021.
Chicago 17th Edition
Carek, Vlado, Magdalena Eger, Ružica Požgaj and Nada Horš. "Citotoksično i genotoksično ispitivanje magnetskih slitina Sm C05." Acta stomatologica Croatica 26, no. 4 (1992): 239-244. https://hrcak.srce.hr/100766
Harvard
Carek, V., et al. (1992). 'Citotoksično i genotoksično ispitivanje magnetskih slitina Sm C05', Acta stomatologica Croatica, 26(4), pp. 239-244. Available at: https://hrcak.srce.hr/100766 (Accessed 16 October 2021)
Vancouver
Carek V, Eger M, Požgaj R, Horš N. Citotoksično i genotoksično ispitivanje magnetskih slitina Sm C05. Acta stomatologica Croatica [Internet]. 1992 [cited 2021 October 16];26(4):239-244. Available from: https://hrcak.srce.hr/100766
IEEE
V. Carek, M. Eger, R. Požgaj and N. Horš, "Citotoksično i genotoksično ispitivanje magnetskih slitina Sm C05", Acta stomatologica Croatica, vol.26, no. 4, pp. 239-244, 1992. [Online]. Available: https://hrcak.srce.hr/100766. [Accessed: 16 October 2021]

Abstracts
Cytotoxicity and genotoxicity of the samarium cobalt alloys were studied on an eukaryotic indicator organism of Saccharomyces cerevisiae D7 in an in vitro system and by a micronucleus test on rat bone marrow in an in vivo system. Alloys were incubated in a 0.01 M phosphate buffer at 37°C for 48 hours. Cells from exponential and early stationary phases of growth were separately incubated in the buffer at 37°C for 2 hours in aerobic conditions. After treatment, cells were washed and resuspended in the buffer, seeded on solid nutritive medium for survival assessment, and on selective medium for evaluation of the frequency of mutation. For micronucleus test analysis, rats were twice intraperitoneally injected with 2 ml of the buffer previously incubated with the alloy. Animals were sacrificed after 24 hours. Results obtained suggested the alloys, used as a tool of retention in mobile prosthetics, to elicit no cytotoxic effects, whereas genotoxic effects were within the allowed limits of experimental error.

Keywords
alloy; toxicity; magnetic retention

Hrčak ID: 100766

URI
https://hrcak.srce.hr/100766

[croatian]

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