Izvorni znanstveni članak
Quantitative Evaluation of the Immunoglobulin G, A and M in the Human Dental Pulp
Greta Škaljac-Staudt
; Zavod za dentalnu patologiju Stomatološkog fakulteta u Zagrebu, Zagreb, Hrvatska
Ivana Ciglar
; Zavod za dentalnu patologiju Stomatološkog fakulteta u Zagrebu, Zagreb, Hrvatska
Jozo Šutalo
; Zavod za dentalnu patologiju Stomatološkog fakulteta u Zagrebu, Zagreb, Hrvatska
Dubravka Čvorišćec
; Zavod za kliničko laboratorijsku dijagnostiku KBC-a u Zagrebu, Zagreb, Hrvatska
Sažetak
The presence o f immunoglobulins G, A and M was studied in human dental pulps using a quantitative method of radial immunodiffusion. Valid data on the amounts of IgG, IgA and IgM were obtained on the basis of measured concentrations of immunoglobulins in each pulp sample and their correlation with total protein concentrations. The results indicated IgG to be present in 100%, IgA in 15% and IgM in 8% o f 13 pulp samples affected by chronic inflammation. The mean values of IgG, IgA and IgM thus determined were 84.3, 4.4 and 1.4 mg/g protein, respectively. In intact pulp tissue, however, no presence o f immunoglobulins G, A and M could be detected using the same method as above. The results obtained suggested the possibility of local synthesis of immunoglobulins in chronically inflamed pulp tissue, indicated that nonspecific inflammatory reaction may have occurred concurrently with some specific immunoglogic reactions. The predominance o f IgG pointed to immunologic reactions o f early types II and III hypersensitivity.
Ključne riječi
Hrčak ID:
100778
URI
Datum izdavanja:
15.1.1991.
Posjeta: 855 *