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Croatica Chemica Acta, Vol.77 No.1-2 Svibanj 2004.

Izvorni znanstveni članak

Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule

Vladimir Paar ; Department of Physics, Faculty of Science, University of Zagreb, Zagreb, Croatia
Nenad Pavin ; Department of Physics, Faculty of Science, University of Zagreb, Zagreb, Croatia
Ivan Basar ; Department of Physics, Faculty of Science, University of Zagreb, Zagreb, Croatia
Marija Rosandić ; Department of Internal Medicine, University Hospital Rebro, Zagreb, Croatia
Ivica Luketin ; Department of Physics, Faculty of Science, University of Split, Split, Croatia
Sonja Durajlija Žinić ; Ru|er Bošković Institute, Zagreb, Croatia

Puni tekst: engleski, pdf (97 KB) str. 73-81 preuzimanja: 198* citiraj
APA 6th Edition
Paar, V., Pavin, N., Basar, I., Rosandić, M., Luketin, I. i Durajlija Žinić, S. (2004). Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule. Croatica Chemica Acta, 77 (1-2), 73-81. Preuzeto s https://hrcak.srce.hr/102648
MLA 8th Edition
Paar, Vladimir, et al. "Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule." Croatica Chemica Acta, vol. 77, br. 1-2, 2004, str. 73-81. https://hrcak.srce.hr/102648. Citirano 15.12.2018.
Chicago 17th Edition
Paar, Vladimir, Nenad Pavin, Ivan Basar, Marija Rosandić, Ivica Luketin i Sonja Durajlija Žinić. "Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule." Croatica Chemica Acta 77, br. 1-2 (2004): 73-81. https://hrcak.srce.hr/102648
Harvard
Paar, V., et al. (2004). 'Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule', Croatica Chemica Acta, 77(1-2), str. 73-81. Preuzeto s: https://hrcak.srce.hr/102648 (Datum pristupa: 15.12.2018.)
Vancouver
Paar V, Pavin N, Basar I, Rosandić M, Luketin I, Durajlija Žinić S. Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule. Croatica Chemica Acta [Internet]. 2004 [pristupljeno 15.12.2018.];77(1-2):73-81. Dostupno na: https://hrcak.srce.hr/102648
IEEE
V. Paar, N. Pavin, I. Basar, M. Rosandić, I. Luketin i S. Durajlija Žinić, "Spectral Densities and Frequencies in the Power Spectrum of Higher Order Repeat Alpha Satellite in Human DNA Molecule", Croatica Chemica Acta, vol.77, br. 1-2, str. 73-81, 2004. [Online]. Dostupno na: https://hrcak.srce.hr/102648. [Citirano: 15.12.2018.]

Sažetak
Fast Fourier transform was applied to the central segment of a fully sequenced genomic segment from the centromeric region in human chromosome 7 (GenBank/AC017075.8, 193277 bp), which is characterized by alpha satellite higher order repeats (HOR). Frequencies and spectral densities were computed for all prominent peaks in the Fourier spectrum. We have additionally introduced a peak to noise ratio as effective spectral density in order to account for frequency variations of the noise level. We have shown that a very good description of computed Fourier frequencies can be obtained by using the multiple formula with the fundamental frequency corresponding to the 2734-bp HOR sequence. The peak at f16 corresponds to the 171-bp monomer. Above the frequency f16, the most pronounced peaks are mostly at multiples of f16 (monomer-multiples). The lowest sixteen monomer-multiples kf16 are locally dominant in spectral densities. The first monomer-multiple that is not locally dominant in spectral density is at k = 17. Above k = 27, the maximum of spectral density is systematically shifted to several neighboring higher frequency multiples. On the basis of the Fourier spectrum, the 171-bp monomer unit was subdivided into three approximately 57-bp subrepeats, which were further subdivided into 12-bp, 14-bp and 17-bp basic subrepeats.

Ključne riječi
human DNA; alpha satellite; higher order repeat; Fourier spectrum

Hrčak ID: 102648

URI
https://hrcak.srce.hr/102648

Posjeta: 329 *