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Croatian medical journal, Vol. 54 No. 3, 2013.

Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2013.54.286

Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina

Lejla Kovačević ; Faculty of Pharmacy, University in Sarajevo, Sarajevo, Bosnia and Herzegovina
Vera Fatur-Cerić ; Faculty of Pharmacy, University in Sarajevo, Sarajevo, Bosnia and Herzegovina
Negra Hadžić ; Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and Herzegovina
Jasmina Čakar ; Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and Herzegovina
Dragan Primorac ; University of Split, School of Medicine and Department of Forensic Science, Split, Croatia
Damir Marjanović ; Genos Ltd, Zagreb, Croatia

Puni tekst: engleski, pdf (92 KB) str. 286-290 preuzimanja: 266* citiraj
APA 6th Edition
Kovačević, L., Fatur-Cerić, V., Hadžić, N., Čakar, J., Primorac, D. i Marjanović, D. (2013). Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina. Croatian medical journal, 54 (3), 286-290. https://doi.org/10.3325/cmj.2013.54.286
MLA 8th Edition
Kovačević, Lejla, et al. "Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina." Croatian medical journal, vol. 54, br. 3, 2013, str. 286-290. https://doi.org/10.3325/cmj.2013.54.286. Citirano 24.04.2019.
Chicago 17th Edition
Kovačević, Lejla, Vera Fatur-Cerić, Negra Hadžić, Jasmina Čakar, Dragan Primorac i Damir Marjanović. "Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina." Croatian medical journal 54, br. 3 (2013): 286-290. https://doi.org/10.3325/cmj.2013.54.286
Harvard
Kovačević, L., et al. (2013). 'Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina', Croatian medical journal, 54(3), str. 286-290. doi: https://doi.org/10.3325/cmj.2013.54.286
Vancouver
Kovačević L, Fatur-Cerić V, Hadžić N, Čakar J, Primorac D, Marjanović D. Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina. Croat Med J. [Internet]. 2013 [pristupljeno 24.04.2019.];54(3):286-290. doi: https://doi.org/10.3325/cmj.2013.54.286
IEEE
L. Kovačević, V. Fatur-Cerić, N. Hadžić, J. Čakar, D. Primorac i D. Marjanović, "Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina", Croatian medical journal, vol.54, br. 3, str. 286-290, 2013. [Online]. doi: https://doi.org/10.3325/cmj.2013.54.286

Sažetak
Aim To detect polymorphisms of 23 Y-chromosomal short
tandem repeat (STR) loci, including 6 new loci, in a reference
database of male population of Bosnia and Herzegovina,
as well as to assess the importance of increasing
the number of Y-STR loci utilized in forensic DNA analysis.
Methods The reference sample consisted of 100 healthy,
unrelated men originating from Bosnia and Herzegovina.
Sample collection using buccal swabs was performed in
all geographical regions of Bosnia and Herzegovina in the
period from 2010 to 2011. DNA samples were typed for 23
Y STR loci, including 6 new loci: DYS576, DYS481, DYS549,
DYS533, DYS570, and DYS643, which are included in the
new PowerPlex® Y 23 amplification kit.
Results The absolute frequency of generated haplotypes
was calculated and results showed that 98 samples had
unique Y 23 haplotypes, and that only two samples shared
the same haplotype. The most polymorphic locus was
DYS418, with 14 detected alleles and the least polymorphic
loci were DYS389I, DYS391, DYS437, and DYS393.
Conclusion This study showed that by increasing the
number of highly polymorphic Y STR markers, to include
those tested in our analysis, leads to a reduction of repeating
haplotypes, which is very important in the application
of forensic DNA analysis.

Hrčak ID: 104779

URI
https://hrcak.srce.hr/104779

Posjeta: 365 *