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Original scientific paper

Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1

Lidija Banjac   ORCID icon orcid.org/0000-0003-0567-041X
Vesna Bokan

Fulltext: english, pdf (304 KB) pages 209-213 downloads: 551* cite
APA 6th Edition
Banjac, L. & Bokan, V. (2012). Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1. Acta clinica Croatica, 51. (2.), 209-213. Retrieved from https://hrcak.srce.hr/106162
MLA 8th Edition
Banjac, Lidija and Vesna Bokan. "Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1." Acta clinica Croatica, vol. 51., no. 2., 2012, pp. 209-213. https://hrcak.srce.hr/106162. Accessed 15 May 2021.
Chicago 17th Edition
Banjac, Lidija and Vesna Bokan. "Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1." Acta clinica Croatica 51., no. 2. (2012): 209-213. https://hrcak.srce.hr/106162
Harvard
Banjac, L., and Bokan, V. (2012). 'Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1', Acta clinica Croatica, 51.(2.), pp. 209-213. Available at: https://hrcak.srce.hr/106162 (Accessed 15 May 2021)
Vancouver
Banjac L, Bokan V. Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1. Acta clinica Croatica [Internet]. 2012 [cited 2021 May 15];51.(2.):209-213. Available from: https://hrcak.srce.hr/106162
IEEE
L. Banjac and V. Bokan, "Retinopathy of Prematurity and Serum Level of Insulin-Like Growth Factor-1", Acta clinica Croatica, vol.51., no. 2., pp. 209-213, 2012. [Online]. Available: https://hrcak.srce.hr/106162. [Accessed: 15 May 2021]

Abstracts
The aim of our study was to measure and compare serum insulin-like growth factor-1 (IGF-1) levels at postmenstrual age of 33 weeks between preterm infants with and without retinopathy of prematurity (ROP). ROP occurs in two phases. Low serum levels of IGF-1 during
ROP phase 1 have been found to correlate with the severity of ROP. ROP phase 2 begins around postmenstrual week 33. We conducted a prospective cohort study to measure serum IGF-1 levels in premature infants at postmenstrual age of 33 weeks. The study included all premature infants (N=74), gestational age ≤33 weeks, hospitalized at Department of Neonatology, Clinical Center of Montenegro, from April 2008 to July 2009. The incidence of ROP in the study cohort was 50.7%. Infants with ROP had a significantly lower birth weight and significantly shorter gestational age. The mean level of IGF-1 at postmenstrual age of 33 weeks was 23.7 mcg/L. Study results showed that there was no significant difference in serum IGF-1 level between newborns with and without ROP at postmenstrual age of 33 weeks (in newborns with ROP, it was the beginning of ROP phase 2). A large controlled study with repeated measurement of IGF-1 level in the neonatal period is needed to confirm that restoration of IGF-I level occurs in ROP phase 2, i.e. that the low level of IGF-1 is only a feature of ROP phase 1.

Keywords
Retinopathy of prematurity; Insulin-like growth factor-1; Preterm infants

Hrčak ID: 106162

URI
https://hrcak.srce.hr/106162

[croatian]

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