Medicus, Vol. 22 No. 1_Astma, 2013.
Pregledni rad
Qvar – Ultrafi ne BDP Particles – Safety and Efficiency
Miroslav Samaržija
; Klinika za plućne bolesti "Jordanovac"
Sažetak
Asthma is a chronic inflammatory airway disease that also affects small airways. Inhaled corticosteroids are effective in the treatment of asthma; however, their deposition in small airways is weak. Deposition of new formulations of inhaled orticosteroids with ultrafi ne particles, smaller than 5 μm, in small airways and alveoli is significantly better. Qvar, HFA - beclomethasone dipropionate, is a new formulation of beclomethasone with ultrafine particles. Qvar allows for more than 50% of the drug to be deposited in the lungs, and 2.6 times lower steroid doses are required to achieve the same effect in comparison with conventional inhaled corticosteroids. Qvar achieves equal or better effects with significantly fewer local side eff ects and similar incidence of systemic side effects compared with conventional inhaled corticosteroids.
Ključne riječi
asthma; Qvar; small airways; inhaled corticosteroids
Hrčak ID:
106476
URI
Datum izdavanja:
15.5.2013.
Posjeta: 2.159 *