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The patterns of melanoma presentation

Ira Pavlović-Ružić ; Clinic for radiotherapy and Oncology Clinical Hospital Center Rijeka Krešimirova 42 51000 Rijeka Croatia
Nives Jonjić ; Head Department and Medical school principla Pathology professor, Department for Pathology, Clinical Hospital Center Rijeka and Medical School University of Rijeka
Gordana Zamolo ; Department for Pathology, Clinical Hospital Center Rijeka and Medical School University of Rijeka
Franjo Gruber
Marta Žuvić Butorac ; University of Rijeka
Miljenko Katunarić ; Department for Pathology, Clinical Hospital Center Rijeka and Medical School University of Rijeka
Sanja Pečanić ; Department for Pathology, Clinical Hospital Center Rijeka and Medical School University of Rijeka


Puni tekst: engleski PDF 328 Kb

str. 174-174

preuzimanja: 353

citiraj


Sažetak

There is a global rising incidence of melanoma. For different reasons patterns of incidence, appearance, gender, anatomical distribution and outcome vary in different geographic area. Screening programs leaded to better early detection of melanoma in Australia and some world areas. National Cancer registry and practice data show incidence in Croatia is constantly rising. Despite public education programs about early discovery, in clinics we still see many new advanced stage melanoma.

We analyzed data from 157 patients, cured and followed for 10 years for T1b-T4aN0 skin melanoma. There was a difference in anatomical distribution of melanoma lesions in correlation with patients age (ANOVA test, F=3.51, p=0,009). A higher prevalence of shoulder melanoma in young people was found, and head/neck in old (post-hoc Sheffe test, p=0.038).The T4 lesions were more found in men, and T1 mainly in women (Pearson c2 test, c2 =12.08, p=0.016). There was no difference in Clark level, but significantly higher Breslow stage was found in men (t=-2.52, p=0.013). Men were much prone to have head and neck, body, and shoulder melanoma; women had more melanoma on their legs and arms. Clark and Breslow level were strongly correlated in leg melanoma; head localization had no correlation at all. As conclusion, more attention should be devoted to improve results in melanoma detection in men, especially with the prevalence of body (back), head/neck localization, sometimes not prone to visual detection. Pattern of distribution show also the need for more attention to shoulder melanoma in younger people.

Ključne riječi

cutaneous melanoma; incidence; gender difference

Hrčak ID:

109924

URI

https://hrcak.srce.hr/109924

Datum izdavanja:

29.10.2013.

Posjeta: 867 *