Ostalo
Rheumatoid Arthritis and Erythema Multiforme: A Possible Pathogenetic Link for T-Cell-Mediated Autoimmune and Reactive Skin Diseases?
Mario Vaccaro
; University of Messina
Fabrizio Guarneri
Olga Barbuzza
Serafinella P Cannavo
Sažetak
We present the case of a woman, with a 14 years’ history of rheumatoid arthrtitis, who showed simultaneously gradually appearing, annular, erythematous, itchy patches and exacerbation of the joint symptoms, of one month duration, after a pregnancy. Clinical and histologic features led us to the diagnosis of erythema multiforme. While it is not possible to exclude that the co-occurrence of the two conditions is coincidental, our case suggests the possibility that erythema multiforme is a sign of an ample alteration of the immune system, that may occur in patients with systemic immunologic diseases as a consequence of the action of various triggering factors, such as molecular mimicry between endogenous and exogenous antigens or pregnancy, which is notoriously a period of complex and still largely unexplored alterations of the reactivity of the immune system
Ključne riječi
rheumatoid arthritis; erythema multiforme; molecular mimicry; pregnancy
Hrčak ID:
109926
URI
Datum izdavanja:
29.10.2013.
Posjeta: 1.370 *