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Pregledni rad
https://doi.org/10.5599/admet.1.3.7

The Roles of Doxorubicin in Hepatocellular Carcinoma

Kin Tam ; Faculty of Health Science, University of Macau, Macau, China

Puni tekst: engleski, pdf (668 KB) str. 29-44 preuzimanja: 3.870* citiraj
APA 6th Edition
Tam, K. (2013). The Roles of Doxorubicin in Hepatocellular Carcinoma. ADMET and DMPK, 1 (3), 29-44. https://doi.org/10.5599/admet.1.3.7
MLA 8th Edition
Tam, Kin. "The Roles of Doxorubicin in Hepatocellular Carcinoma." ADMET and DMPK, vol. 1, br. 3, 2013, str. 29-44. https://doi.org/10.5599/admet.1.3.7. Citirano 25.10.2021.
Chicago 17th Edition
Tam, Kin. "The Roles of Doxorubicin in Hepatocellular Carcinoma." ADMET and DMPK 1, br. 3 (2013): 29-44. https://doi.org/10.5599/admet.1.3.7
Harvard
Tam, K. (2013). 'The Roles of Doxorubicin in Hepatocellular Carcinoma', ADMET and DMPK, 1(3), str. 29-44. https://doi.org/10.5599/admet.1.3.7
Vancouver
Tam K. The Roles of Doxorubicin in Hepatocellular Carcinoma. ADMET and DMPK [Internet]. 2013 [pristupljeno 25.10.2021.];1(3):29-44. https://doi.org/10.5599/admet.1.3.7
IEEE
K. Tam, "The Roles of Doxorubicin in Hepatocellular Carcinoma", ADMET and DMPK, vol.1, br. 3, str. 29-44, 2013. [Online]. https://doi.org/10.5599/admet.1.3.7

Sažetak
Liver cancer is the third most common cause of death from cancer worldwide. Hepatocellular carcinoma (HCC) accounts for 80 – 90 % of all primary liver cancers. The mortality of HCC is high, and the treatment options are limited. Doxorubicin exhibits a broad spectrum of anti-tumour activity. When administrated via the hepatic artery, doxorubicin showed anti-tumour effects and partial response in HCC patients. In this mini review, we will first outline the treatment options for HCC. Then, we will briefly discuss the pharmacological, toxicological and pharmacokinetic aspects of doxorubicin. Finally, we will review the new developments and future directions of using doxorubicin in the therapy of HCC.

Ključne riječi
primary liver cancer; anticancer; cytotoxic drug; transarterial chemoembolization; drug eluting beads

Hrčak ID: 112505

URI
https://hrcak.srce.hr/112505

Posjeta: 4.272 *