Pregledni rad

https://doi.org/10.11613/BM.2014.009

Physical activity - an important preanalytical variable

Fabian Sanchis-Gomar ; Department of Physiology, Faculty of Medicine, University of Valencia; Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain
Giuseppe Lippi ; Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Parma, Italy

Sažetak

The concentration of several biochemical and hematological biomarkers is strongly influenced by a number of preanalytical variables. Several lines of evidence attest that short, middle, and long-term exercise, as well as the relative intensity of physical effort (from mild to strenuous), may influence a broad array of laboratory variables. The amount of extracellular release and clearance from blood of most of these biomarkers is markedly influenced by the biological characteristics of the molecule(s), level of training, type, intensity and duration of exercise, and time of recovery after training. It is hence noteworthy that test results that fall outside the conventional reference ranges in athletes not only may reflect the presence of a given disease, but may frequently mirror an adaptation to regular training or changes that have occurred during and/or following strenuous exercise, and which should be clearly acknowledged to prevent misinterpretation of laboratory data. The aim of this narrative review is to provide an update about the most significant changes of some biochemical and hematological biomarkers in response to physical exercise, for appropriate interpretation of these changes in the context of physically active subjects.

Ključne riječi

biomarkers; training; plasma volume; metabolism; cellular damage

Hrčak ID:

115745

URI

https://hrcak.srce.hr/115745

Datum izdavanja:

15.2.2014.

Posjeta: 1.519 *