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Clinical Characteristics of Alopecia Areata in Down syndrome

Juliany Estefan ; Medical Genetics Service, Martagão Gesteira Pediatric Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Mariana Queiroz ; Medical Genetics Service, Martagão Gesteira Pediatric Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ
Fabricio Costa ; 1. Datagenno Interactive Research Ltd., Av. Cardoso Moreira 841, Sala 106, Itaperuna, RJ, Brazil; 2. Cancer Biology and Epigenomics Program, Children’s Memorial Research Center and Northwestern University’s Feinberg School of Medicine, 2300 Children’s
Marcelo Coutinho ; 1. Datagenno Interactive Research Ltd., Av. Cardoso Moreira 841, Sala 106, Itaperuna, RJ, Brazil 2. Clinical Genetics Service, Department of Medical Genetics, Campos dos Goytacazes, RJ, Brazil
Kalynka Higino ; Internal Medicine, Secretaria Municipal de Alto Taquari, MT, Brazil
Juan Llerena Jr ; Medical Genetics Service, Fernandes Figueira Institute – FIOCRUZ, Rio de Janeiro, RJ, Brazil
Fernando Vargas ; Medical Genetics Service, Gafreé-Guinle Hospital – UNIRIO, Rio de Janeiro, RJ, Brazil
Suely Santos ; Medical Genetics Service, Gafreé-Guinle Hospital – UNIRIO, Rio de Janeiro, RJ, Brazil
Mauro Geller ; 1. Medical Genetics Service, Martagão Gesteira Pediatric Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil 2.Department of Neurology (Langone Medical Center) and Department of Dermatology, New York University, NY, USA; 3. I
Márcia Ribeiro ; Medical Genetics Service, Martagão Gesteira Pediatric Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil

Puni tekst: engleski, PDF (144 KB) str. 0-0 preuzimanja: 545* citiraj
APA 6th Edition
Estefan, J., Queiroz, M., Costa, F., Coutinho, M., Higino, K., Llerena Jr, J., ... Ribeiro, M. (2013). Clinical Characteristics of Alopecia Areata in Down syndrome. Acta Dermatovenerologica Croatica, 21 (4), 0-0. Preuzeto s https://hrcak.srce.hr/115999
MLA 8th Edition
Estefan, Juliany, et al. "Clinical Characteristics of Alopecia Areata in Down syndrome." Acta Dermatovenerologica Croatica, vol. 21, br. 4, 2013, str. 0-0. https://hrcak.srce.hr/115999. Citirano 17.10.2021.
Chicago 17th Edition
Estefan, Juliany, Mariana Queiroz, Fabricio Costa, Marcelo Coutinho, Kalynka Higino, Juan Llerena Jr, Fernando Vargas, Suely Santos, Mauro Geller i Márcia Ribeiro. "Clinical Characteristics of Alopecia Areata in Down syndrome." Acta Dermatovenerologica Croatica 21, br. 4 (2013): 0-0. https://hrcak.srce.hr/115999
Harvard
Estefan, J., et al. (2013). 'Clinical Characteristics of Alopecia Areata in Down syndrome', Acta Dermatovenerologica Croatica, 21(4), str. 0-0. Preuzeto s: https://hrcak.srce.hr/115999 (Datum pristupa: 17.10.2021.)
Vancouver
Estefan J, Queiroz M, Costa F, Coutinho M, Higino K, Llerena Jr J i sur. Clinical Characteristics of Alopecia Areata in Down syndrome. Acta Dermatovenerol Croat. [Internet]. 2013 [pristupljeno 17.10.2021.];21(4):0-0. Dostupno na: https://hrcak.srce.hr/115999
IEEE
J. Estefan, et al., "Clinical Characteristics of Alopecia Areata in Down syndrome", Acta Dermatovenerologica Croatica, vol.21, br. 4, str. 0-0, 2013. [Online]. Dostupno na: https://hrcak.srce.hr/115999. [Citirano: 17.10.2021.]

Sažetak

Aim: This study was undertaken to better understand clinical characteristics, environmental and physical events in Down syndrome (DS) and alopecia areata (AA). Material and Methods: Cross-sectional study was performed with 18 individuals with DS who were currently presenting or had presented AA. Were evaluated: gender, age, local and type of AA, presence of autoimmune disease or atopy, AA in first-degree relatives, environmental, physical and clinical intercurrences. Results: Average age was 11.6 years (y) (SD ± 5.5y) and average age of AA onset was 7.2y (2.5 to 15.2y). The duration of alopecia episodes varied; an average of 2.7y (0.1 to 18.7y) was observed. Recurrence of AA was reported in 27.7% (5/18) and the average number of recurrences was 3.6. Localized type, was seen in 83.4% of individuals, and the most frequent location was scalp (100%). Seven of the individuals presented atopy. Fourteen of the individuals had undergone environmental and/or clinical intercurrences. Conclusion: The most frequent presentation of AA in DS is the non-recurrent, localized form, on scalp, with varied period of duration. Changes in individuals’ routine, occurred in more than half of the studied group. We suggest further studies of the psychology and immunogenetics of the etiopathology of AA in DS.

Ključne riječi
Alopecia areata; Down syndrome

Hrčak ID: 115999

URI
https://hrcak.srce.hr/115999

Posjeta: 761 *