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Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus

Iveta [imi Šimić ; University of Zagreb, University Hospital Center Zagreb, Department of Internal Medicine, Zagreb, Croatia
Ivan Pećin ; University of Zagreb, University Hospital Center Zagreb, Department of Internal Medicine, Zagreb, Croatia
Eugenia Tedeschi-Reiner ; University of Zagreb, University Hospital Center »Sestre milosrdnice«, Department of Ophtalmology, Zagreb, Croatia
Ozren Zrinšćak ; University of Zagreb, University Hospital Center »Sestre milosrdnice«, Department of Ophtalmology, Zagreb, Croatia
Nediljko Šućur ; University of Zagreb, University Hospital Center Zagreb, Department of Internal Medicine, Zagreb, Croatia
Željko Reiner ; University of Zagreb, University Hospital Center Zagreb, Department of Internal Medicine, Zagreb, Croatia

Puni tekst: engleski, pdf (101 KB) str. 783-787 preuzimanja: 248* citiraj
APA 6th Edition
Šimić, I.[., Pećin, I., Tedeschi-Reiner, E., Zrinšćak, O., Šućur, N. i Reiner, Ž. (2013). Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus. Collegium antropologicum, 37 (3), 783-787. Preuzeto s https://hrcak.srce.hr/118218
MLA 8th Edition
Šimić, Iveta [imi, et al. "Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus." Collegium antropologicum, vol. 37, br. 3, 2013, str. 783-787. https://hrcak.srce.hr/118218. Citirano 25.01.2021.
Chicago 17th Edition
Šimić, Iveta [imi, Ivan Pećin, Eugenia Tedeschi-Reiner, Ozren Zrinšćak, Nediljko Šućur i Željko Reiner. "Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus." Collegium antropologicum 37, br. 3 (2013): 783-787. https://hrcak.srce.hr/118218
Harvard
Šimić, I.[., et al. (2013). 'Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus', Collegium antropologicum, 37(3), str. 783-787. Preuzeto s: https://hrcak.srce.hr/118218 (Datum pristupa: 25.01.2021.)
Vancouver
Šimić I[, Pećin I, Tedeschi-Reiner E, Zrinšćak O, Šućur N, Reiner Ž. Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus. Collegium antropologicum [Internet]. 2013 [pristupljeno 25.01.2021.];37(3):783-787. Dostupno na: https://hrcak.srce.hr/118218
IEEE
I.[. Šimić, I. Pećin, E. Tedeschi-Reiner, O. Zrinšćak, N. Šućur i Ž. Reiner, "Risk Factors for Microvascular Atherosclerotic Changes in Patients with Type 2 Diabetes Mellitus", Collegium antropologicum, vol.37, br. 3, str. 783-787, 2013. [Online]. Dostupno na: https://hrcak.srce.hr/118218. [Citirano: 25.01.2021.]

Sažetak
Diabetes mellitus is a metabolic disorder primarily characterized by elevated blood glucose levels and by microvas- cular and macrovascular complications which increase the morbidity and mortality.The aim of this study was to assess whether in high risk patients with type 2 diabetes mellitus whose blood pressure and lipid levels are well controlled still exist risk factors for microvascular changes and target organ damage (nephropathy and retinopathy). In this case con- trol retrospective study 326 patients (111 with nephropathy and/or retinopathy and 215 controls) were enrolled. Nephro- pathy or retinopathy was present in 10.1% and 26.9% cases, respectively. Only 71% of patients (no significant difference between cases and controls) were treated with antidiabetic drugs. Therefore their diabetes was not properly controlled (hemoglobin A1c was 7.96% in cases and 7.58% in controls). Patients with microvascular changes had significantly lon- ger diabetes than the controls (p < 0.05) but there were no significant differences between these two groups concerning lipids concentrations. Statins and fibrates were used by significantly less (p < 0.05) patients with microvascular compli- cations than by those without them (21.6% vs. 36.3% and 1.8% vs. 17.2% respectively). The results of this study suggest that the duration of the disease and adequate control of glycaemia in patients with type 2 diabetes mellitus are more im- portant for microvascular complications than the serum lipoproteins levels. Lipid-lowering treatment might have an im- pact on microvascular complications in patients with type 2 diabetes, irrespectively of their serum lipid levels.

Ključne riječi
cardiovascularrisk; type2diabetesmellitus; cholesterol,LDL-cholesterol; HDL-cholesterol,statins,fibrates

Hrčak ID: 118218

URI
https://hrcak.srce.hr/118218

Posjeta: 427 *