Medicina, Vol. 50 No. 1, 2014.
Pregledni rad
The basics of bone biology
Luka Đudarić
; Zavod za anatomiju, Medicinski fakultet Sveučilišta u Rijeci
Sanja Zoričić Cvek
; Zavod za anatomiju, Medicinski fakultet Sveučilišta u Rijeci
Olga Cvijanović
; Zavod za anatomiju, Medicinski fakultet Sveučilišta u Rijeci
Ariana Fužinac-Smojver
; Zavod za anatomiju, Medicinski fakultet Sveučilišta u Rijeci
Tanja Ćelić
; Zavod za anatomiju, Medicinski fakultet Sveučilišta u Rijeci
Danijela Martinović
Sažetak
Bone tissue is the most abundant supporting tissue in the human body. It builds the skeletal system, which performs several functions: it provides the framework of the body, determines the size and shape of the body, protects the organs, and enables movements. Bone tissue develops from the mesenchyme by a complex process of osteogenesis. Osteogenesis results from continuous processes of bone formation and resorption. Bone formation and resorption are, considering their purpose as whole, synergistically and physiologically balanced processes since they both act to create and maintain the skeletal system homeostasis. Physiological imbalance of these processes is evident as pathological osteogenesis when bone tissue homeostasis is disturbed, regardless of the cause (osteoarthrosis, osteoporosis). Many recent investigations have focused on the study of these processes and their results provided understanding of pathophysiological processes which affect bone tissue. The results of investigating osteoinduction (bone morphogenetic proteins and their inhibitors) and osteoconduction have found successful application in bone surgery.
Ključne riječi
bone remodeling; bone tissue; osteogenesis
Hrčak ID:
118495
URI
Datum izdavanja:
3.3.2014.
Posjeta: 13.996 *