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Review article

Production of Antibodies in Chickens

Mojca Narat ; Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Groblje 3, SI-1230 Domžale, Slovenia

Fulltext: english, pdf (110 KB) pages 259-267 downloads: 4.134* cite
APA 6th Edition
Narat, M. (2003). Production of Antibodies in Chickens. Food Technology and Biotechnology, 41 (3), 259-267. Retrieved from
MLA 8th Edition
Narat, Mojca. "Production of Antibodies in Chickens." Food Technology and Biotechnology, vol. 41, no. 3, 2003, pp. 259-267. Accessed 7 Dec. 2021.
Chicago 17th Edition
Narat, Mojca. "Production of Antibodies in Chickens." Food Technology and Biotechnology 41, no. 3 (2003): 259-267.
Narat, M. (2003). 'Production of Antibodies in Chickens', Food Technology and Biotechnology, 41(3), pp. 259-267. Available at: (Accessed 07 December 2021)
Narat M. Production of Antibodies in Chickens. Food Technology and Biotechnology [Internet]. 2003 [cited 2021 December 07];41(3):259-267. Available from:
M. Narat, "Production of Antibodies in Chickens", Food Technology and Biotechnology, vol.41, no. 3, pp. 259-267, 2003. [Online]. Available: [Accessed: 07 December 2021]

Chickens, as a source of desired antibodies, represent an alternate animal system that offers some advantages with respect to animal care, high productivity and special suitability of avian antibodies for certain diagnostic purposes. Despite being an excellent counterpart
to mammal IgG chicken IgY antibodies still represent an underused resource. This may be due to the lack of information concerning the possibility of production and application of IgY or their use is being hampered by problems with keeping the chickens and with IgY isolation. As a suggestion how to overcome IgY isolation problems a new immunoaffinity isolation method is presented here. The main purpose of the present work is to provide information on developments and possibilities in the production of chicken IgY.
Polyclonal, monoclonal and recombinant forms of IgY, successfully produced so far, as well as their applications are summarised. This article should be a contribution to the efforts of the European Centre for the Validation of Alternative Methods (ECVAM), whose main goal is to promote the scientific and regulatory acceptance of alternative methods, which are of importance to the bioscience and which reduce, refine or replace the use of laboratory animals.

chicken egg yolk; antibodies; phage display; antibody library; transgenic chickens; immunoglobulin transport

Hrčak ID: 118637


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