Paediatria Croatica, Vol. 57 No. 3, 2013.
Izvorni znanstveni članak
Acute respiratory infections in children caused by adenoviruses and parainfluenza viruses
Gordana Mlinarić Galinović
; Odjel za virologiju, Služba za mikrobiologiju, Hrvatski zavod za javno zdrav stvo i Medicinski fakultet Sveučilišta u Zagrebu
Gorana Šulentić Tomić
; Odjel za virologiju, Služba za mikrobiologiju, Hrvatski zavod za javno zdrav stvo i Medicinski fakultet Sveučilišta u Zagrebu
Renata Sim
; Odjel za virologiju, Služba za mikrobiologiju, Hrvatski zavod za javno zdrav stvo i Medicinski fakultet Sveučilišta u Zagrebu
Leo Markovinović
; Klinika za infektivne bolesti „Dr. Fran Mihaljević“ i Medicinski fakultet Sveučilišta u Zagrebu, Zagreb
Goran Tešović
; Klinika za infektivne bolesti „Dr. Fran Mihaljević“ i Medicinski fakultet Sveučilišta u Zagrebu, Zagreb
Jasna Čepin Bogović
; Klinika za dječje bolesti Zagreb, Klinika za pedijatriju
Irena Ivković Jureković
; Klinika za dječje bolesti Zagreb, Klinika za pedijatriju
Sažetak
All around the globe, acute respiratory infections in children and adults are often caused by parainfl uenza viruses and adenovi
ruses.
The aim of this study was to analyze epidemiological characteristics of acute respiratory infections in children caused by aden
ovi-
ruses and parainfl uenza viruses in Zagreb and Zagreb County. The study included inpatients aged up to 10 years from Zagreb and
Zagreb County suff
ering from acute respiratory infections, treated during the period from November 14, 2008 to November 14, 2010.
Nasopharyngeal secretion was obtained from each study patient. The viruses were detected by direct immunofl uorescence. The
study comprised 528/2403 (21.97%) children with acute respiratory infections who were positive for adenoviruses or parainfl uenz
a
viruses (adenoviruses in 448/2403 (18.64%) and parainfl uenza viruses in 80/2403 (3.33%) cases). Among positive cases, 306/528
(58%) were male and 222/528 (42%) female, yielding a male to female ratio 1:0.73. Adenoviruses were proved in 448/528 (85%) and
parainfl uenza viruses in 80/528 (15%) patients. The number of cases of adenoviruses or parainfl uenza viruses infection signifi c
antly
increased at the age over 12 months and gradually decreased after the age of 2 years. The prevalence of adenoviruses and parain
-
fl uenza viruses infection was highest in children aged 1-2 years. Adenoviral infections appeared throughout the year, with a pe
ak in
spring (especially in March). The most common clinical presentation of adenoviruses and parainfl uenza viruses infections in chi
ld-
hood was upper respiratory tract infection followed by pneumonia, bronchiolitis, bronchitis and croup. The results of the study
showed that adenoviruses infections were more frequent than those caused by parainfl uenza viruses and that both viruses were
important causes of upper respiratory tract infections and pneumonia in children aged 1-5 years
Ključne riječi
adenoviruses; parainfl uenza viruses 2, human; respiratory tract infections; infant, newborn; child, preschool; child
Hrčak ID:
119703
URI
Datum izdavanja:
30.9.2013.
Posjeta: 1.050 *