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Kratko priopćenje
https://doi.org/10.2478/acph-2014-0026

Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology

SHUMIN LAN ; Department of Pharmacy, Guangdong No.2 Provincial People’s Hospital, Guangzhou 510317, PR China
JINGMING LIN ; Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, PR China
NI ZHENG ; Department of Pharmacy, Guangdong No.2 Provincial People’s Hospital, Guangzhou 510317, PR China

Puni tekst: engleski, pdf (893 KB) str. 369-378 preuzimanja: 410* citiraj
APA 6th Edition
LAN, S., LIN, J. i ZHENG, N. (2014). Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology. Acta Pharmaceutica, 64 (3), 369-378. https://doi.org/10.2478/acph-2014-0026
MLA 8th Edition
LAN, SHUMIN, et al. "Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology." Acta Pharmaceutica, vol. 64, br. 3, 2014, str. 369-378. https://doi.org/10.2478/acph-2014-0026. Citirano 18.10.2019.
Chicago 17th Edition
LAN, SHUMIN, JINGMING LIN i NI ZHENG. "Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology." Acta Pharmaceutica 64, br. 3 (2014): 369-378. https://doi.org/10.2478/acph-2014-0026
Harvard
LAN, S., LIN, J., i ZHENG, N. (2014). 'Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology', Acta Pharmaceutica, 64(3), str. 369-378. https://doi.org/10.2478/acph-2014-0026
Vancouver
LAN S, LIN J, ZHENG N. Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology. Acta Pharm. [Internet]. 2014 [pristupljeno 18.10.2019.];64(3):369-378. https://doi.org/10.2478/acph-2014-0026
IEEE
S. LAN, J. LIN i N. ZHENG, "Evaluation of the antioxidant activity of Coreopsis tinctoria Nuff. and optimisation of isolation by response surface methodology", Acta Pharmaceutica, vol.64, br. 3, str. 369-378, 2014. [Online]. https://doi.org/10.2478/acph-2014-0026

Sažetak
The aim of the present study was to determine the antioxidant activity of Coreopsis tinctoria flowering tops (CTFT). Studies were conducted to obtain suitable extraction conditions for chlorogenic acid, quercetin, luteolin, apigenin and kaempferol, which were identified and quantified by HPLC. Response surface methodology was employed to optimise the ultrasound-assisted extraction conditions, including extraction time, ethanol concentration and liquid-solid ratio. The antioxidant activity of the extracts was analysed using various antioxidant models, such as DPPH, ABTS and hydroxyl radical scavenging assay. CTFT extracted for 15.0 min with ethanol at a concentration of 60.4 % and with liquid-solid ratio 27.5:1 possessed a considerable amounts of total flavonoids and polyphenols (18.9 %). This extract showed higher scavenging activity of ABTS and hydroxyl radical activity than rutin, however not in the DPPH test. We may assume that CTFT possess antioxidant and free radical scavenging potentials.

Ključne riječi
Coreopsis tinctoria (Asteraceae); flavonoids; polyphenols; antioxidant activity; response surface methodology; HPLC

Hrčak ID: 121070

URI
https://hrcak.srce.hr/121070

Posjeta: 531 *