hrcak mascot   Srce   HID

Acta Pharmaceutica, Vol. 64 No. 4, 2014.

Kratko priopćenje
https://doi.org/10.2478/acph-2014-0040

Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots

DELAIR SILVEIRA DOS SANTOS ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil
JÚLIA VIEIRA OBERGER ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil
RIVALDO NIERO ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil
THEODORO WAGNER ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil
FRANCO DELLE MONACHE ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil
ALEXANDRE BELLA CRUZ ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil
ZHELMY MARTIN-QUINTAL ; Universidad Autónoma de Yucatán (UADY) Calle 41 No 421 x 26 y 28 Col. Industrial, C.P. 97150, Mérida, Yucatán, Mexico
VALDIR CECHINEL FILHO ; Programa de Pós-Graduação em Ciências Farmacêuticas e Núcleo de Investigações Químico-Farmacêuticas (NIQFAR)-Universidade do Vale do Itajaí, 88302-202, Itajaí, SC, Brazil

Puni tekst: engleski, pdf (491 KB) str. 495-501 preuzimanja: 585* citiraj
APA 6th Edition
DOS SANTOS, D.S., OBERGER, J.V., NIERO, R., WAGNER, T., DELLE MONACHE, F., CRUZ, A.B., ... FILHO, V.C. (2014). Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots. Acta Pharmaceutica, 64 (4), 495-501. https://doi.org/10.2478/acph-2014-0040
MLA 8th Edition
DOS SANTOS, DELAIR SILVEIRA, et al. "Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots." Acta Pharmaceutica, vol. 64, br. 4, 2014, str. 495-501. https://doi.org/10.2478/acph-2014-0040. Citirano 23.02.2019.
Chicago 17th Edition
DOS SANTOS, DELAIR SILVEIRA, JÚLIA VIEIRA OBERGER, RIVALDO NIERO, THEODORO WAGNER, FRANCO DELLE MONACHE, ALEXANDRE BELLA CRUZ, ZHELMY MARTIN-QUINTAL i VALDIR CECHINEL FILHO. "Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots." Acta Pharmaceutica 64, br. 4 (2014): 495-501. https://doi.org/10.2478/acph-2014-0040
Harvard
DOS SANTOS, D.S., et al. (2014). 'Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots', Acta Pharmaceutica, 64(4), str. 495-501. doi: https://doi.org/10.2478/acph-2014-0040
Vancouver
DOS SANTOS DS, OBERGER JV, NIERO R, WAGNER T, DELLE MONACHE F, CRUZ AB i sur. Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots. Acta Pharm. [Internet]. 2014 [pristupljeno 23.02.2019.];64(4):495-501. doi: https://doi.org/10.2478/acph-2014-0040
IEEE
D.S. DOS SANTOS, et al., "Seasonal phytochemical study and antimicrobial potential of Vetiveria zizanioides roots", Acta Pharmaceutica, vol.64, br. 4, str. 495-501, 2014. [Online]. doi: https://doi.org/10.2478/acph-2014-0040

Sažetak
This paper describes the seasonal phytochemical variation and the antimicrobial potential of V. zizanioides roots collected in Brazil. Considering the high levels of chemical constituents and their biological activity in dichloromethane fraction, the plants were grown in different seasons and the respective dichloromethane fractions were analyzed by gas chromatography-mass spectrometry. The antimicrobial activity was evaluated against several pathogenic microorganisms by determining the minimum inhibitory concentration (MIC) by the agar dilution method. The yields of dichloromethane fractions from plants collected in the autumn and spring occurred in a higher proportion than in other seasons. Khusimol (2) was isolated by column chromatography and identified by NMR and CG-MS, along with other sesquiterpenes, including β-vetivenene (1), vetiselinenol (3), isovalencenol (4), vetivenic acid (5), α-vetivone (6) and β-vetivone (7). Some extracts showed promising antimicrobial effects, with MICs ranging from 31.25 to 500 μg mL–1. Kushimol was slightly active against the tested microorganisms.

Ključne riječi
Vetiveria zizanioides (Poaceae); seasonality; sesquiterpenes; khusimol; antimicrobial activity

Hrčak ID: 123218

URI
https://hrcak.srce.hr/123218

Posjeta: 710 *