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Original scientific paper

The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.

Mirna Brkljačić ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Marin Torti ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Jelka Pleadin ; Croatian Veterinary Institute, Zagreb, Croatia
Vladimir Mrljak ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Iva Šmit ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Ivana Kiš ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Iva Mayer ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Martina Crnogaj ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia
Vesna Matijatko ; Clinic for Internal Diseases, Faculty of Veterinary Medicine, Univesity of Zagreb, Zagreb, Croatia

Fulltext: english, pdf (235 KB) pages 575-589 downloads: 365* cite
APA 6th Edition
Brkljačić, M., Torti, M., Pleadin, J., Mrljak, V., Šmit, I., Kiš, I., ... Matijatko, V. (2014). The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.. Veterinarski arhiv, 84 (6), 575-589. Retrieved from https://hrcak.srce.hr/130258
MLA 8th Edition
Brkljačić, Mirna, et al. "The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.." Veterinarski arhiv, vol. 84, no. 6, 2014, pp. 575-589. https://hrcak.srce.hr/130258. Accessed 15 Jan. 2021.
Chicago 17th Edition
Brkljačić, Mirna, Marin Torti, Jelka Pleadin, Vladimir Mrljak, Iva Šmit, Ivana Kiš, Iva Mayer, Martina Crnogaj and Vesna Matijatko. "The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.." Veterinarski arhiv 84, no. 6 (2014): 575-589. https://hrcak.srce.hr/130258
Harvard
Brkljačić, M., et al. (2014). 'The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.', Veterinarski arhiv, 84(6), pp. 575-589. Available at: https://hrcak.srce.hr/130258 (Accessed 15 January 2021)
Vancouver
Brkljačić M, Torti M, Pleadin J, Mrljak V, Šmit I, Kiš I, et al. The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.. Veterinarski arhiv [Internet]. 2014 [cited 2021 January 15];84(6):575-589. Available from: https://hrcak.srce.hr/130258
IEEE
M. Brkljačić, et al., "The concentrations of the inflammatory markers the amino-terminal portion of C-type pronatriuretic peptide and procalcitonin in canine babesiosis caused by Babesia canis.", Veterinarski arhiv, vol.84, no. 6, pp. 575-589, 2014. [Online]. Available: https://hrcak.srce.hr/130258. [Accessed: 15 January 2021]

Abstracts
Canine babesiosis is a multisystemic protozoan disease, considered as sepsis with a wide range of clinical signs, which can result in various outcomes, from mild to fatal. In veterinary medicine there are still no specific biomarkers for sepsis, therefore the aim of this study was to investigate markers widely used in human medicine, but poorly in veterinary medicine and never in canine babesiosis. Ninety-seven dogs were included in this study, among which 72 were diagnosed for babesiosis and 25 were healthy and used as the control group. Concentrations of procalcitonin (PCT) and the amino-terminal portion of C-type pronatriuretic peptide (NT-pCNP) were determined for each dog. There was a significant difference in PCT concentrations between the healthy and the babesiosis group before and after the antibabesial treatment, but there were no significant differences between the dogs that survived and the dogs that died. In contrast, there was no significant difference in NT-pCNP concentrations between the healthy and babesiosis groups before and after the antibabesial treatment, but there were significant differences between the dogs that survived and the dogs that died. It may be concluded that as in human medicine, PCT is most probably a good marker for both detection and grading of SIRS complications developed only in bacterial induced systemic infections, whereas NT-pCNP can be considered a good prognostic pro-inflammatory marker of outcome in canine babesiosis.

Keywords
babesiosis; dog; inflammatory marker; C-type pronatriiuretic peptide; procalcitonin; outcome

Hrčak ID: 130258

URI
https://hrcak.srce.hr/130258

[croatian]

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