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Veterinarski arhiv, Vol. 85 No. 1, 2015.

Izvorni znanstveni članak

The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.

Kadry M. Sadek ; Department of Biochemistry, Faculty of Veterinary Medicine, Damanhur University, Egypt
Hazem M. Shaheen ; Department of Pharmacology, Faculty of Veterinary Medicine, Damanhur University, Egypt

Puni tekst: engleski, pdf (303 KB) str. 95-103 preuzimanja: 358* citiraj
APA 6th Edition
Sadek, K.M. i Shaheen, H.M. (2015). The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.. Veterinarski arhiv, 85 (1), 95-103. Preuzeto s https://hrcak.srce.hr/135344
MLA 8th Edition
Sadek, Kadry M. i Hazem M. Shaheen. "The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.." Veterinarski arhiv, vol. 85, br. 1, 2015, str. 95-103. https://hrcak.srce.hr/135344. Citirano 18.01.2019.
Chicago 17th Edition
Sadek, Kadry M. i Hazem M. Shaheen. "The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.." Veterinarski arhiv 85, br. 1 (2015): 95-103. https://hrcak.srce.hr/135344
Harvard
Sadek, K.M., i Shaheen, H.M. (2015). 'The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.', Veterinarski arhiv, 85(1), str. 95-103. Preuzeto s: https://hrcak.srce.hr/135344 (Datum pristupa: 18.01.2019.)
Vancouver
Sadek KM, Shaheen HM. The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.. Veterinarski arhiv [Internet]. 2015 [pristupljeno 18.01.2019.];85(1):95-103. Dostupno na: https://hrcak.srce.hr/135344
IEEE
K.M. Sadek i H.M. Shaheen, "The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition.", Veterinarski arhiv, vol.85, br. 1, str. 95-103, 2015. [Online]. Dostupno na: https://hrcak.srce.hr/135344. [Citirano: 18.01.2019.]

Sažetak
This study investigated the effect of an antiparasitic ivermectin (IVM) drug on the endocrine reproductive hormones of twenty healthy adult 250-350 kg Baladi cows that were 4-7 years of age. The cows were divided into two groups (n = 10 each). The first was a control group injected with physiological saline; the second group was treated with the recommended therapeutic dose of IVM (0.2 mg/kg, s/c) one day after parturition. Blood samples were taken on the 1st, 15th, 30th and 90th day after IVM treatment. The results revealed that IVM injection at one day after parturition delayed estrous for up to 3 months (absence of estrous signs and rectal palpation revealed no ovarian structures). IVM significantly (P<0.05) decreased serum follicular stimulating hormone (FSH), luteinizing hormone (LH) and estradiol for up to 3 months. In addition, IVM significantly (P<0.05) increased serum progesterone, prolactin and cortisol for up to 3 months. Further, IVM caused unobservable changes in serum testosterone and sex hormones binding globulin. Serum calcium levels significantly increased on the 1st day of IVM injection, while serum phosphorus significantly decreased on the15th and 30th day of IVM injection. It was concluded that IVM delayed estrous in cows for three months via disturbances in the female reproductive hormones and calcium/phosphorus homeostasis. Therefore, it is recommended that IVM should not be injected directly after parturition. Furthermore, the increased calcium after IVM indicates that an overdose of IVM should not be counteracted by calcium therapy; instead, any other antiallergic preparation could be used.

Ključne riječi
cows; ivermectin; mineral homeostasis; post parturition; reproductive hormones

Hrčak ID: 135344

URI
https://hrcak.srce.hr/135344

[hrvatski]

Posjeta: 495 *