Izvorni znanstveni članak

Left Ventricular Systolic Function in Selected Type 1 Diabetic Patients with or without Diabetic Retinopathy and Microalbuminuria

Kajo Bućan ; Clinical Department of Ophthalmology, Split University Hospital Center, Split, Croatia
Lovro Bojić ; Clinical Department of Ophthalmology, Split University Hospital Center, Split, Croatia
Damir Fabijanić ; Clinical Department of Cardiology, Split University Hospital Center, Split, Croatia
Davor Galetović ; Clinical Department of Ophthalmology, Split University Hospital Center, Split, Croatia
Vesna Čapkun ; Clinical Department of Nuclear Medicine, Split University Hospital Center, Split, Croatia
Dobrila Karlica Utrobičić ; Clinical Department of Ophthalmology, Split University Hospital Center, Split, Croatia
Ivona Bućan ; School of Medicine, University of Split, Split, Croatia

Sažetak

Vascular endothelial dysfunction is a basic etiologic factor for the development of late clinical complications in patients with diabetes mellitus type 1, such as diabetic retinopathy, diabetic nephropathy (which is characterized at the very beginning by microalbuminuria), and left ventricular cardiac dysfunction. The aims of this study were to determine the prevalence of asymptomatic left ventricular systolic dysfunction in patients with diabetes mellitus type 1 and with or without diabetic retinopathy and microalbuminuria, and to correlate the duration of diabetes with the dynamics of diabetic retinopathy, microalbuminuria and asymptomatic left ventricular dysfunction development in these patients. One-hundred and twenty selected patients with diabetes mellitus type 1 were examined by ophthalmologist and cardiologist. All patients underwent ergometric testing and two-dimensional (2-D) echocardiography with pulsed Doppler. Patients were divided into three groups according to their fundus findings and microalbuminuria: (1) patients without diabetic retinopathy and without microalbuminuria (n=40); (2) patients with diabetic retinopathy without microalbuminuria (n=40); and (3) patients with diabetic retinopathy and microalbuminuria (n=40). All three groups of patients with diabetes mellitus type 1 (with low cardiovascular risk, regulated blood sugar, and without diabetic neuropathy) had echocardiographic values in the normal range. We found no statistically significant correlation between the duration of diabetes mellitus type 1 and echocardiographic values.

Ključne riječi

Diabetes mellitus, type 1; Retinopathy; Albuminuria; Ventricular function, left

Hrčak ID:

136615

URI

https://hrcak.srce.hr/136615

Datum izdavanja:

1.12.2014.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.448 *