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Professional paper

The estimation of comorbidities and serum concentration of cardiac biomarkers in patients with chronic obstructive pulmonary disease treated with invasive or nonivasive ventilation

Sven Pal ; Dom zdravlja Primorsko-goranske županije, Rijeka
Danijel Knežević ; Katedra za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Janja Kuharić ; Katedra za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Alan Šustić ; Katedra za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Vlatka Sotošek Tokmadžić ; Katedra za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet Sveučilišta u Rijeci, Rijeka
Antonija Harjač ; Opća bolnica Varaždin, Varaždin
Robert Marčun ; Sveučilišna bolnica za plućne bolesti i alergije Golnik, Golnik, Slovenija
Mitja Lainščak ; Sveučilišna bolnica za plućne bolesti i alergije Golnik, Golnik, Slovenija

Fulltext: croatian, pdf (915 KB) pages 0-0 downloads: 352* cite
APA 6th Edition
Pal, S., Knežević, D., Kuharić, J., Šustić, A., Sotošek Tokmadžić, V., Harjač, A., ... Lainščak, M. (2015). Utvrđivanje komorbiditeta i serumske koncentracije srčanih biomarkera u pacijenata s kroničnom opstruktivnom plućnom bolesti liječenih invazivnom ili neinvazivnom ventilacijom. Medicina Fluminensis, 51 (2), 0-0. Retrieved from https://hrcak.srce.hr/139475
MLA 8th Edition
Pal, Sven, et al. "Utvrđivanje komorbiditeta i serumske koncentracije srčanih biomarkera u pacijenata s kroničnom opstruktivnom plućnom bolesti liječenih invazivnom ili neinvazivnom ventilacijom." Medicina Fluminensis, vol. 51, no. 2, 2015, pp. 0-0. https://hrcak.srce.hr/139475. Accessed 18 Jan. 2021.
Chicago 17th Edition
Pal, Sven, Danijel Knežević, Janja Kuharić, Alan Šustić, Vlatka Sotošek Tokmadžić, Antonija Harjač, Robert Marčun and Mitja Lainščak. "Utvrđivanje komorbiditeta i serumske koncentracije srčanih biomarkera u pacijenata s kroničnom opstruktivnom plućnom bolesti liječenih invazivnom ili neinvazivnom ventilacijom." Medicina Fluminensis 51, no. 2 (2015): 0-0. https://hrcak.srce.hr/139475
Harvard
Pal, S., et al. (2015). 'Utvrđivanje komorbiditeta i serumske koncentracije srčanih biomarkera u pacijenata s kroničnom opstruktivnom plućnom bolesti liječenih invazivnom ili neinvazivnom ventilacijom', Medicina Fluminensis, 51(2), pp. 0-0. Available at: https://hrcak.srce.hr/139475 (Accessed 18 January 2021)
Vancouver
Pal S, Knežević D, Kuharić J, Šustić A, Sotošek Tokmadžić V, Harjač A, et al. Utvrđivanje komorbiditeta i serumske koncentracije srčanih biomarkera u pacijenata s kroničnom opstruktivnom plućnom bolesti liječenih invazivnom ili neinvazivnom ventilacijom. Medicina Fluminensis [Internet]. 2015 [cited 2021 January 18];51(2):0-0. Available from: https://hrcak.srce.hr/139475
IEEE
S. Pal, et al., "Utvrđivanje komorbiditeta i serumske koncentracije srčanih biomarkera u pacijenata s kroničnom opstruktivnom plućnom bolesti liječenih invazivnom ili neinvazivnom ventilacijom", Medicina Fluminensis, vol.51, no. 2, pp. 0-0, 2015. [Online]. Available: https://hrcak.srce.hr/139475. [Accessed: 18 January 2021]

Abstracts
Aim: To determine the most common comorbidities in patients with chronic obstructive pulmonary disease (COPD) treated with invasive or nonivasive ventilation, investigate serum concentration of cardiac biomarkers (N-terminal pro-brain natriuretic peptide or NT-proBNP and troponin) in these patients and analyze if type of ventilation affects serum concentrations of cardiac biomarkers. Patients and methods: We analyzed 41 medical records of patients with acute exacerbation of COPD treated with nonivasive or invasive ventilation in University hospital for pulmonary disease and alergies Golnik. Results: The most common comorbidities were arterial hypertension, chronic heart failure and ischemic heart disease. In COPD patients with acute exacerbation treated with nonivasive ventilation NT-proBNP levels were elevated in 23 (100 %) patient and troponin levels were elevated in 3 (14 %) patients. In COPD patients with acute exacerbation treated with invasive ventilation NT-proBNP levels were elevated in 17 (94 %) patients and troponin levels were elevated in 7 (39 %) patients. When comparing NT-proBNP and troponin levels between COPD patients with acute exacerbation treated with noninvasive ventilation and those treated with invasive ventilation the statistically significant difference was not found. Discussion and conclusion: Taking into consideration the common risk factors for development od COPD and cardiovascular diseases, in combination with anatomical and functional relation that exists between cardiovascular and pulmonary system, it is not unusual that this two conditions occur with high prevalence in the same patients. Because of the similar clinical manifestations it is important to actively search for these conditions in order to achieve optimal treatment for the patients.

Keywords
chronic obstructive pulmonary disease; heart failure; myocardial ischemia; NT-proBNP; troponin

Hrčak ID: 139475

URI
https://hrcak.srce.hr/139475

[croatian]

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