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Depression and Dementia in Parkinson’s Disease

Osman Sinanović orcid id orcid.org/0000-0001-8957-7284 ; Clinical Department of Neurology, Tuzla University Clinical Center, Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina
Josip Hudić ; Clinical Department of Neurology, Tuzla University Clinical Center, Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina
Sanela Zukić ; Clinical Department of Neurology, Tuzla University Clinical Center, Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina
Almasa Kapidžić ; Clinical Department of Neurology, Tuzla University Clinical Center, Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina
Lejla Zonić ; Clinical Department of Neurology, Tuzla University Clinical Center, Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina
Mirjana Vidović ; Clinical Department of Neurology, Tuzla University Clinical Center, Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina


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str. 73-75

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Sažetak

Parkinson’s disease (PD) is a neurodegenerative disorder causing not only motor dysfunction but also cognitive, psychiatric, autonomic and sensory disturbances. Depression is the most common psychiatric disturbance identified in patients with PD and has been shown to be more common in PD than in other chronic and disabling disorders, occurring in approximately 40% of PD patients. However, the prevalence and clinical features associated with depression in PD remain controversial. Dementia is increasingly recognized as a symptom associated with idiopathic PD, and is found in up to 40% of all patients suffering from that condition. The aim of this study was to estimate the prevalence of depressive and dementia symptoms in PD patients. The study included 35 consecutive patients with PD, 13 (37.4%) male and 22 (62.6%) female (mean age 62.9}11.0, range 36-85 years), mean duration of disease 4.7}2.9 (range 1-10) years, hospitalized during one year at Clinical Department of Neurology, Tuzla University Clinical Center, Tuzla, Bosnia and Herzegovina. The Mini Mental State Examination (MMSE) was used for assessment of cognitive deterioration and Beck Depression Inventory (BDI) for depression. Computerized tomography was performed in all patients. According to BDI scale, depressive symptoms were present in all 35 PD patients: minimal in 4 (11.4%), low in 7 (20%), moderate in 8 (22.8%), severe in 9 (25.4%) and extreme in 7 (20%) patients. On MMSE scale, 9 (25.4%) patients were free from cognitive deterioration and 26 (74.6%) patients had moderate to severe deterioration, but 21 (60%) patients (7 (33.33%) male and 14 (66.66%) female) had symptoms of dementia (MMSE score ≤23). Using MMSE scale, 8 (22.8%) patients were free from dementia and 27 (77.2%) patients had some cognitive deterioration. Very mild symptoms of dementia were found in 6 (25.9%) and overt features of dementia in 21 (74.1%) PD patients. So, out of 35 PD study patients, 21 (60%) (7 (33.3%) male and 14 (66.7%) female) had symptoms of dementia (MMSE score ≤23). In conclusion, depressive and dementia symptoms arecommon in PD patients.

Ključne riječi

Depression; Dementia; Parkinson’s disease

Hrčak ID:

141596

URI

https://hrcak.srce.hr/141596

Datum izdavanja:

1.3.2015.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.870 *