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Recenzija, Prikaz
https://doi.org/10.13112/PC.2014.40

Immature colonic ganglion cells as a cause of megacolon in infancy: case report

Danijela Jojkić Pavkov
Melanija Vislavski
Nada Vučković
Bojana Petrovački
Matilda Djolai
Smiljana Marinković
Milena Mitrović

Puni tekst: engleski, pdf (100 KB) str. 227-229 preuzimanja: 808* citiraj
APA 6th Edition
Jojkić Pavkov, D., Vislavski, M., Vučković, N., Petrovački, B., Djolai, M., Marinković, S. i Mitrović, M. (2014). Immature colonic ganglion cells as a cause of megacolon in infancy: case report. Paediatria Croatica, 58 (3), 227-229. https://doi.org/10.13112/PC.2014.40
MLA 8th Edition
Jojkić Pavkov, Danijela, et al. "Immature colonic ganglion cells as a cause of megacolon in infancy: case report." Paediatria Croatica, vol. 58, br. 3, 2014, str. 227-229. https://doi.org/10.13112/PC.2014.40. Citirano 10.08.2020.
Chicago 17th Edition
Jojkić Pavkov, Danijela, Melanija Vislavski, Nada Vučković, Bojana Petrovački, Matilda Djolai, Smiljana Marinković i Milena Mitrović. "Immature colonic ganglion cells as a cause of megacolon in infancy: case report." Paediatria Croatica 58, br. 3 (2014): 227-229. https://doi.org/10.13112/PC.2014.40
Harvard
Jojkić Pavkov, D., et al. (2014). 'Immature colonic ganglion cells as a cause of megacolon in infancy: case report', Paediatria Croatica, 58(3), str. 227-229. https://doi.org/10.13112/PC.2014.40
Vancouver
Jojkić Pavkov D, Vislavski M, Vučković N, Petrovački B, Djolai M, Marinković S i sur. Immature colonic ganglion cells as a cause of megacolon in infancy: case report. Paediatria Croatica [Internet]. 2014 [pristupljeno 10.08.2020.];58(3):227-229. https://doi.org/10.13112/PC.2014.40
IEEE
D. Jojkić Pavkov, et al., "Immature colonic ganglion cells as a cause of megacolon in infancy: case report", Paediatria Croatica, vol.58, br. 3, str. 227-229, 2014. [Online]. https://doi.org/10.13112/PC.2014.40

Sažetak
IImmaturity of ganglion cells is a rare form of dysganglionosis that belongs to the group of dysmorphic types, characterized by a
normal or mildly decreased number of ganglion cells, with the cells and their nuclei being considerably smaller in size. The disorder
usually manifests clinically early after birth with abdominal distension, vomiting, feeding intolerance, and delayed passing of meconium.
Diagnostic evaluation may include radiological studies; however, biopsy of colonic mucosa with histochemical analysis is
considered the most reliable method. Manometry is a reliable noninvasive diagnostic study to confi rm motility disorder. Treatment
may be medical in mild cases and more commonly surgical due to complications of the disorder. We present a case of immature
colonic ganglion cells as a cause of megacolon in infancy. In our case, medicamentous treatment was eff ective and led to normalization
of bowel emptying and stool consistency. Considering that follow up rectosigmoidoscopy was refused by the patient’s parents,
we were not able to compare the histopathologic fi ndings before and after the medicamentous treatment; however, the favorable
clinical course made us assume that the ganglion cells had probably fully matured.

Ključne riječi
colon; ganglia; dygestive system abnormalities; megacolon; infant

Hrčak ID: 142305

URI
https://hrcak.srce.hr/142305

[hrvatski]

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