Pregledni rad
Photorejuvenation – Topical Photodynamic Therapy as Therapeutic Opportunity for Skin Rejuvenation
Ines Sjerobabski Masnec
orcid.org/0000-0003-4224-7522
; University Department of Dermatovenerology, University Hospital Center “Sestre milosrdnice”, Zagreb, Croatia
Mirna Šitum
; University Department of Dermatovenerology, University Hospital Center “Sestre milosrdnice”, Zagreb, Croatia
Sažetak
The intrinsic aging process of the skin in unavoidable and depends on the passage of time per se. Among harmful
environmental factors that contribute to extrinsic aging, long-term effects of repeated exposure to ultraviolet radiation are
the most signifi cant and are referred to as photoaging. Photoaging is directly correlated to the quantity of UV rays received
during the course of a lifetime. Topical photodynamic therapy is well-established procedure for the treatment of actinic
keratoses, Bowen disease and basal cell carcinomas. Clinical experience has demonstrated that extensive treatment of
actinic keratoses on sun-damaged skin also produces as a positive side effects signifi cant improvement of the signs of skin
aging. An improvement of lentigines, skin roughness, fi ne lines, increases in skin smoothness and improvement of actinic
elastosis, skin colour and reduction of hyperpigmentation were seen. The reversible side effects of photodynamic therapy
include pain, erythema, oedema, scaling and crusting, and sometimes in darker skin types post-infl ammatory hyperpigmentation.
Photodynamic therapy is promising approach for treatment of photoinduced skin aging and takes place between
ablative and non-ablative methods for skin rejuvenation. Effective improvement of photoaged skin, the possibility of repeated
treatments and imitated side effects makes photodynamic therapy a promising procedure for skin rejuvenation.
Ključne riječi
photoaging; photodynamic therapy; photosensitizer; photorejuvenation
Hrčak ID:
147447
URI
Datum izdavanja:
26.12.2014.
Posjeta: 676 *