Acta clinica Croatica, Vol. 41 No. 1, 2002.
Izvorni znanstveni članak
Effect of Duration and Type of Diabetes on Cerebral Hemodynamics
Marinko Dikanović
Dragutin Kadojić
Marica Jandrić
Milan Bitunjac
Lidija Marijanović
Sažetak
A group of 100 patients aged 48-67 years, with a diagnosis of diabetes mellitus, and control group of 100 healthy subjects were examined by transcranial Doppler sonography, a modern and sophisticated diagnostic method for visualization of hemodynamic changes in basal cerebral arteries in real time. The aim of the study was to determine hemodynamic changes in cerebral arteries in diabetic patients, and to analyze the effect of duration and type of diabetes on cerebrovascular disease. The rate of transcranial Doppler sonography abnormalities was statistically significantly higher in diabetic patients than in control subjects (55% vs. 11%, 2=, p<0.05). The duration and type of diabetes were found to have an impact on the development of pathologic cerebrovascular changes. Hemodynamic impairments were more common in type 1 than in type 2 diabetes patients (72.5% vs. 43.3%). The study suggested the duration of diabetes to predict for the development of atherosclerotic processes in cerebral vessels. Atherosclerotic changes were found in 34.0% and 71.4% of patients suffering from diabetes for <5 and ≥5 years, respectively. In all diabetic patients, signs of cerebral microangiopathy were significantly more commonly recorded than those of cerebral macroangiopathy.
Ključne riječi
Cerebrovascular disorders, etiology; Diabetic angiopathies, complications; Diabetes mellitus, complications; Risk factors; Ultrasonography, Doppler, transcranial
Hrčak ID:
14704
URI
Datum izdavanja:
1.3.2002.
Posjeta: 1.172 *